Human Peripheral Blood Mononuclear Cells

Pinpoint immune function with freshly-collected, viable PBMCs


Optimize and customize with patient-centric collection

Patients donate whole blood in the comfort of their own homes. PBMCs are isolated within 24 hours of venipuncture collection, cryopreserved, and stored in liquid nitrogen.


Average cell viability ≥ 95%


Isolation from whole blood

Final Product

Aliquots of 5-10 million cells

Rely on our standard protocols or customize to your specifications:

  • Dedicated study coordinator keeps you in the loop
  • Further isolation into  T cells, B cells, and/or NK cells
  • 4 field, 11 loci Human Leukocyte Antigen (HLA) typing available
  • Collect fresh plasma or serum simultaneously

Partner with Sanguine

Compliance & Quality Assured

Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval of all study protocols, specific study documentation, and study participant facing information.  Both Advarra and WCG IRB are organized and operates in compliance with: FDA, OHRP, and International Conference on Harmonization (ICH).

Sanguine operates under an electronic informed consent process which executes 21 CFR part 11 compliant e-signatures, and Sanguine systems interacting with study participant information are HIPAA-compliant.

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More than Biospecimen Procurement

Take advantage of our experienced and dedicated sample collection, logistics, processing, characterization, and storage capabilities to optimize and streamline your study design and mitigate unnecessary variability.

Publications using Sanguine PBMCs:


Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs


Nature Communications

Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1


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