Rare diseases are a paradoxic — they are both uncommon and common. And understanding them may help us to gain insights into more ordinary diseases.
If a disease affects fewer than 200,000 people in the United States, it is considered a rare disease. But there are an estimated 5,000 to 8,000 rare diseases. In a country with 329.5 million people, this means roughly 1 in 10 Americans likely has a rare disease.1 And more than 300 million people globally are estimated to live with a rare disease.
Mark Cuban's New Online Pharmacy Supplies Generic Drugs at Low Costs
Disruptive technologies have the power to rapidly transform industries often yielding considerable benefits to consumers. Platforms like Uber and Airbnb have completely changed the landscape of transportation and travel to the benefit of consumers, while also causing collateral damage to traditional taxi drivers and hotel industries, respectively. Most recently, Mark Cuban has endeavored to take on the prescription drug industry – trying to make generic drugs more affordable for consumers. He has launched his own online pharmacy, called Mark Cuban Cost Plus Drug Company (MCCPDC) to tackle the rising costs of prescription generic drugs.
Longitudinal assessment of
adhesion to vascular cell adhesion
molecule-1 at steady state and
during vaso-occlusive crises in
sickle cell disease
White, Callaghan, Gao et al
Br J Haematol (2021) 196 (4), 1052-1058
Flow adhesion of whole blood to
P-selectin: a prognostic biomarker
for vaso-occlusive crisis in sickle
Hines, Callaghan, Zaidi et al
Br J Haematol (2021)