HELP ACCELERATE RESEARCH FOR
Prospective Longitudinal Collection of Whole Blood from Subjects Diagnosed with Myelofibrosis or Essential Thrombocythemia
Location: United States
Length: 30-45 minutes
Regeneron Pharmaceuticals (Regeneron) is analyzing whole blood from subjects with myelofibrosis or essential thrombocythemia. This will help scientists to more deeply understand the disease and support additional clinical research and treatment efforts. This protocol aims to provide researchers with biospecimens from individuals diagnosed with myelofibrosis or essential thrombocythemia.
You can participate if you:
- Are 18 years of age or older
- Have been diagnosed with Myelofibrosis or Essential Thrombocythemia
- Have a documented calreticulin (CALR) gene mutation
You cannot participate if you:
- Are pregnant
- Have a known history of HIV, hepatitis, or other infectious diseases
- Experienced excess blood loss including blood donation defined
as 250 mL in the last month or 500 mL in the last two months
Sanguine's Expertise in Accelerating Research
How It Works
Once you have signed up to participate in a research study, one of our research coordinators will reach out to conduct an over-the-phone screening that takes about 10-15 minutes.
During the screen, you will be asked questions about your health and demographic information.
Informed Consent and Documentation
Once you are deemed eligible to participate in a study, you will be emailed an Informed Consent Form (ICF).
Informed Consent is the most important aspect of any research study as it outlines and confirms research participants' rights. The ICF may be signed electronically.
After all proper documentation is on file, we will schedule your at-home appointment with one of our trained, licensed phlebotomists.
On the day of your appointment, please make sure to be hydrated and follow all instructions provided by your research coordinator.
At the end of your appointment, you will receive a $100 visa gift card for your contribution.
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research from home. Our goal is to develop innovative solutions that empower patients to participate in research for conditions that matter most to them, regardless of their location or ability to travel.
We work directly with patients and advocacy groups to accelerate research through convenience and transparency while guiding each patient every step of the way.
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Got a question?
As a thank you for your time, we will provide you with a $100 Visa gift card for each home visit you participate in. You will receive the gift card immediately after the at-home appointment is completed.
You can withdraw from the study or decline participation at any time without providing a reason.
The reasons are endless. By participating in an at-home research study, you are part of a process that may help researchers detect diseases earlier, and develop new therapeutics, diagnostics, and treatments that may save thousands of people each year.
Yes. However, to participate in most studies, you will need to provide proof of your diagnosis. Even if you are not currently seeing a physician, you can still sign an authorization for Medical Record Release from your former physician that can serve as proof of diagnosis. Previous medical records can serve as proof of diagnosis.
Once you sign up, we will review your health profile and contact you if you might qualify for a research study. If you may qualify for a study, a research coordinator will contact you within 48 hours to confirm your health information and tell you more about what is required to participate in a certain study. When you are ready to be scheduled, your clinical research coordinator will work with you to schedule an at-home visit. One of Sanguine’s mobile health staff members will meet you in the privacy and comfort of your home to explain the research study and perform the sample collection.
After you provide your basic health information, we will review your health profile within 48 hours to see if you might qualify for a research study. If you do not qualify for any of our current studies when you sign up, we will keep your contact information on file and reach out when we have a study that matches your health profile.
When a research coordinator calls you, he/she will ask you questions regarding your medical history to determine if you qualify for any of our current studies. He/she will also walk you through the Informed Consent process and what you should expect going forward. Depending on the study, we may ask you to sign a Release of Medical Records so that we can provide the researchers with additional information they need to conduct their study. Please have your physician’s contact information available.
In order to participate in any condition-specific research study, you must provide proof of your diagnosis, which may include: - a copy of your medical records - a visit summary from a doctor’s appointment - a medical diagnostic report - a bill from your insurance company with your name and diagnosis Certain studies may require additional documentation. Your clinical research coordinator will inform you if this is the case.
We may ask you to sign a Release of Medical Records so that we can provide researchers with the data they need to conduct as comprehensive of a study as possible. Your de-identified medical information will help translate laboratory results from collected samples into clinical information that may be used to develop new therapies and/or diagnostics.
All of our mobile health staff undergo an extensive background check and screening process, ensuring that only the most experienced and trusted mobile health staff are a part of the Sanguine team.
No. We collect blood and other samples from donors in order to provide scientists with quality samples for their research. We do not perform diagnostic tests.
We provide samples to researchers around the world. When you participate, your sample is sent to the lab to be processed, or directly to the researchers to be analyzed for their studies.
For your safety and the protection of your privacy, Sanguine’s mobile health staff will only meet you at your place of residence. Certain circumstances may permit Sanguine staff to meet you at your place of work. These are evaluated internally on a case-by-case basis. Please let your clinical research coordinator know if you are uncomfortable participating from your home.
Preparation varies depending on the type of appointment. Your research coordinator will review preparation needed before your appointment. For appointments that require blood draws, hydration is very important. Not being sufficiently hydrated can make it difficult to find a vein. Drink at least 2 glasses of water before your appointment. In addition, please refrain from drinking alcohol 24 hours prior to your blood draw.
When you are scheduled for an appointment with one of our trained mobile health staff, you will receive a confirmation email containing your appointment date and time, along with the name of your mobile health staff member.
The appointment may take anywhere from 30 to 90 minutes, depending on the study. While most appointments only take 30 minutes, each participant is unique and circumstances may vary.
If you need to reschedule or cancel your appointment for any reason, please call or email your assigned mobile health staff member as soon as possible. If you cannot get in contact with him/her, please call us at (818) 804 2462.
Our mobile health staff are very punctual and will arrive at your appointment within 10 minutes of the allotted time. If a staff member expects to arrive outside of this window, they will call you directly. If 10 minutes has passed and you have not heard from him/her, please call us at (818) 804 2462.