Frontotemporal Dementia PBMC

Frontotemporal Dementia PBMC

Frontotemporal Dementia PBMC is collected from IRB-consented donors diagnosed with clinically confirmed Frontotemporal Dementia (FTD). These peripheral blood mononuclear cell (PBMC) samples are ideal for profiling peripheral immune cells involved in neuroinflammation and neurodegeneration. PBMCs from FTD donors are valuable for studying immune dysregulation, transcriptomics, and neurodegenerative disease mechanisms.

Product Features

  • Cryopreserved, clinically verified FTD PBMC samples
  • Cryopreserved to ensure stability and long-term storage
  • Research Use Only (RUO)

De-identified Donor Data

  • Clinically confirmed FTD diagnosis
  • Donor demographics: age, sex assigned at birth, ethnicity
  • Medical and treatment history available when applicable

Applications

  • Profiling peripheral immune cells involved in neuroinflammation and neurodegeneration
  • Biomarker discovery and validation
  • Transcriptomic, proteomic, or functional studies
  • Custom assay development and disease modeling

Compliance and Quality

  • IRB-approved collection and electronic informed consent
  • HIPAA-compliant donor data handling

Ordering and Customization

Frontotemporal Dementia PBMC is available in standard and custom volumes. Contact learnmore@sanguinebio.com for international requests or documentation needs.

Protocols & Documentation

  • PBMC Isolation from Whole Blood

    Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.

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  • Immune Cell Isolation

    Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.

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  • Choosing the Right PBMC Configuration

    Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.

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  • Thawing Cryopreserved PBMC

    Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.

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  • Informed Consent Form (ICF)

    Available upon request — confirms donor consent for research use and downstream commercialization.

PBMC

Frequently Asked Questions

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Do samples come with donor screening reports?

1 Answer

All our samples have self-reported infectious disease testing and verified clinical diagnosis. Many of our samples have the option of electronic medical records provided and our prospective collection offers the opportunity for patient reported outcomes and surveys. Learn more here. https://sanguinebio.com/patient-reported-outcomes-pro-surveys-questionnaires/

YES – Certificate of analysis is available upon request.

Lead times vary from ready to ship inventory to prospective studies.

International shipping is available. We also work with a number of distributors. Contact us to discuss options at learnmore@sanguinebio.com.

We have several ordering methods. You can order directly online with a PO or credit card or contact us to have a sales specialist help with your order. https://sanguinebio.com/request-quote/

You can request a quote on this page or contact us at learnmore@sanguinebio.com. https://sanguinebio.com/request-quote/

NO – no minimum order requirements.

For bulk pricing inquiries, please contact: LearnMore@sanguinebio.com

YES – Fresh leukopaks can be delivered same day in select locations. Often, leukopaks are shipped same day as collection, thus arriving next day.

Contact learnmore@sanguinebio.com for current inventory. The website states “over 150 verified-conditions from ready-to-ship to prospective collections.” View our ready to ship products: https://sanguinebio.com/products/?pro_inventory=inventory

YES – Matched samples across multiple matrices are available, including synovial fluid are available.

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Need a custom PBMC cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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