Frontotemporal Dementia PBMC
About: Frontotemporal Dementia PBMC - IRB-consented PBMC samples collected from donors diagnosed with Frontotemporal Dementia. Suitable for profiling peripheral immune cells involved in neuroinflammation and neurodegeneration.
Frontotemporal Dementia PBMC
Frontotemporal Dementia PBMC is collected from IRB-consented donors diagnosed with clinically confirmed Frontotemporal Dementia (FTD). These peripheral blood mononuclear cell (PBMC) samples are ideal for profiling peripheral immune cells involved in neuroinflammation and neurodegeneration. PBMCs from FTD donors are valuable for studying immune dysregulation, transcriptomics, and neurodegenerative disease mechanisms.
Product Features
- Cryopreserved, clinically verified FTD PBMC samples
- Cryopreserved to ensure stability and long-term storage
- Research Use Only (RUO)
De-identified Donor Data
- Clinically confirmed FTD diagnosis
- Donor demographics: age, sex assigned at birth, ethnicity
- Medical and treatment history available when applicable
Applications
- Profiling peripheral immune cells involved in neuroinflammation and neurodegeneration
- Biomarker discovery and validation
- Transcriptomic, proteomic, or functional studies
- Custom assay development and disease modeling
Compliance and Quality
- IRB-approved collection and electronic informed consent
- HIPAA-compliant donor data handling
Ordering and Customization
Frontotemporal Dementia PBMC is available in standard and custom volumes. Contact learnmore@sanguinebio.com for international requests or documentation needs.
Protocols & Documentation
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PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
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Electronic medical records are an option to be included with the PBMC sample, as well as, flow cytometry and other phenotypic testing.
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YES – we can often accommodate treatment-naive samples including various cancers, and you can specify immunosupression status or other requirements in the I/E criteria.
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Self-reported infectious disease testing is always available and some of our products have additional testing.
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HLA-typing is available for some of our PBMC products.
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YES to both – Unique donors can be specified, and multiple vials from the same donor can be arranged. You can specify these requirements when ordering.
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Healthy PBMCs achieve over 90% vialbity post-thaw. Although our disease-state PBMCs are processed with same stringent SOP, there is more variability depending upon disease. Learn more about our post thaw viability here. https://sanguinebio.com/pbmc-viability-quality-assurance/
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Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.