Covid-19 PBMC

High-Quality PBMCs for Covid-19 Research

Covid-19 Human PBMC products are sourced from donors clinically diagnosed with Covid-19 and processed under stringent conditions to support immunology research. These cryopreserved peripheral blood mononuclear cells (PBMCs) enable studies on immune dysregulation, cytokine response, and therapeutic screening for Covid-19-related inflammation.

Product Features

  • Research Use Only (RUO), cryopreserved PBMC
  • Clinically confirmed Covid-19 donors
  • Available in cell counts ranging from 5 million to 2 billion
  • Processed within 24 hours of collection
  • Stored using CryoStor® CS10 freezing media
  • IRB-approved protocols and electronic informed consent
  • Screen LeukoLot™ available prior to bulk orders

De-identified Donor Data

  • Verified Covid-19 diagnosis
  • Donor demographics: age, sex assigned at birth, race/ethnicity
  • Self-reported allergies and infectious disease history
  • Additional Covid-19-specific data available upon request

Applications

  • Biomarker discovery and validation
  • Drug screening and therapeutic development
  • Immune pathway analysis in Covid-19 pathophysiology
  • Transcriptomic and proteomic profiling

Quality and Compliance

  • IRB-approved collections and protocols
  • 21 CFR Part 11 – compliant e-consent system
  • HIPAA-compliant donor data protection

Ordering & Shipping

Covid-19 PBMC samples are shipped on dry ice and available in custom aliquots. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com to confirm documentation and compliance needs.

Protocols & Documentation

  • PBMC Isolation from Whole Blood

    Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.

    Download
  • Immune Cell Isolation

    Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.

    Download
  • Choosing the Right PBMC Configuration

    Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.

    Download
  • Thawing Cryopreserved PBMC

    Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.

    Download
  • Informed Consent Form (ICF)

    Available upon request — confirms donor consent for research use and downstream commercialization.

Covid-19 Publications

PBMC

Frequently Asked Questions

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Do PBMCs come with flow cytometry data, clinical patient information, or treatment status details?

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Electronic medical records are an option to be included with the PBMC sample, as well as, flow cytometry and other phenotypic testing.

YES – we can often accommodate treatment-naive samples including various cancers, and you can specify immunosupression status or other requirements in the I/E criteria.

Self-reported infectious disease testing is always available and some of our products have additional testing.

HLA-typing is available for some of our PBMC products.

YES to both – Unique donors can be specified, and multiple vials from the same donor can be arranged. You can specify these requirements when ordering.

Healthy PBMCs achieve over 90% vialbity post-thaw. Although our disease-state PBMCs are processed with same stringent SOP, there is more variability depending upon disease. Learn more about our post thaw viability here. https://sanguinebio.com/pbmc-viability-quality-assurance/

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Need a custom PBMC cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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