PBMC

PBMC

In Stock · 500

About: Human PBMCs for Research: Human PBMC samples are collected from healthy and clinically confirmed disease-state donors, then cryopreserved to preserve viability and function. Sanguine’s PBMCs are designed to support a wide range of research applications, from immune profiling and cytokine analysis to cell-based assays and therapeutic development.

IRB-approved Worldwide shipping Full donor metadata

In Stock Samples

Lot # Condition Cell Count (M) Race/Ethnicity Age Gender Country of Collection Medications Vials Price Action
77952 Normal (Healthy) 100M Caucasian 55 Female US
Adderall 15mg
 54 $578.00
77887 Discoid Lupus Erythematosus (DLE) 10M African American 54 Female United States
Amlodipine 10mg QD Ibuprofen 600mg PRN Excedrin extra strength PRN Vitamin D 5000 units QD Biotin Gummy 10000mcg BID
 5
77383 Vitiligo 10M Caucasian 76 Male United States
Humalog Cartridge 3mL 25 units QD Cyanocobalamin 10000mcg/ml Inj. 1 mL every 3 weeks Potassium Cl 20meq ER Tablets 1 QD Calcitriol 0.25 mcg Capsules 1 QD Fludrocortisone 0.1 mg Tablets 1 QD Levothyroxine 0.05mg (50mcg) Tablets 1 QD Hydrocortisone 5mg Tablets 15 mg Q.A.M and 5mg Q.P.M. Calcium citrate-vitamin D 315 mg-250 unit 2 QD Iron (Ferrous Sulfate) 325 (65 Fe) MG Tablet 1 QD Magnesium oxide 400 mg tablet 1 QD
 1
75207 Psoriatic Arthritis 5M Hispanic/Latino 75 Female US 8 $765.00
74944 Osteoarthritis 23M Caucasian 72 Male United States
Levothryoxine/175mcg/QD, Flomax 4mg x2/daily Metoprolol 50mg Amlodipine 5mg Pepcid OTC Azelastine hydrochloride .05 eye drops Flonase - when needed
 1
74801 Allergy 10M Caucasian 61 Female United States
Current: cellcept mycophenolate 2500mg QD nifedipine 30mg QD Multivitamin Previous: omeprazole 20 mg
 4 $530.00
74037 Celiac Disease 50M Caucasian 28 Female
Orlissa/150mg/QD Synthroid/5mcg/QD Insulin pump
 57 $1,109.00
74328 Vitiligo 10M African American 47 Female US
Levothyroxine 110mcg, amlodipine 10mg, atorvastatin 20mg
 5
52562 Peanut Allergy 10M Caucasian 33 Female
Singulair 10 mg QD Symbicort QD Q-Var epi pen PRN
 6 $530.00
79411 Normal (Healthy) 100M Other 33 Female US
No medications
 14 $578.00
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High-Quality PBMCs for Research

Human PBMCs are sourced from healthy and disease-state donors and processed under controlled conditions to support high-quality research. These cryopreserved peripheral blood mononuclear cells enable studies in immune function, cytokine response, biomarker discovery, cell therapy research, and therapeutic screening.

Whether you need PBMCs as matched controls, disease-state comparators, or custom donor-defined samples, Sanguine helps research teams source PBMCs aligned to protocol requirements and downstream assay needs.

What Is a PBMC?

Human PBMCs (peripheral blood mononuclear cells) are the round-nucleus immune cells — lymphocytes, monocytes, and dendritic cells — isolated from whole blood or a leukopak, and one of the most widely used starting materials in immunology and cell therapy research. For a full primer, see our guide to human PBMCs.

Product Features

  • Research use only cryopreserved human PBMCs
  • Sourced from healthy and disease-state donors
  • Available in cell counts ranging from 5 million to 2 billion
  • Processed within 24 hours of collection
  • Preserved using CryoStor CS10 freezing media
  • Designed to support cell viability and functional assays
  • IRB-approved protocols and electronic informed consent
  • Screening and bulk-order support available for larger PBMC programs

De-identified Donor Data

Available donor-level information helps researchers select PBMC samples that align to study design and population requirements.

  • Donor demographics including age, sex assigned at birth, and race/ethnicity
  • Self-reported allergies and infectious disease history
  • Healthy donor and disease-state context where applicable
  • Additional donor-specific data available upon request
  • Study-specific donor requirements may be supported for custom programs

Applications

Human PBMCs support a broad range of immunology and translational research workflows.

  • Biomarker discovery and validation
  • Drug screening and therapeutic development
  • Immune pathway analysis
  • Cytokine and functional immune assays
  • Transcriptomic and proteomic profiling
  • Cell-based assay development
  • Matched control and disease-state comparison studies

Disease-State & Patient PBMCs

Sanguine supplies disease-state PBMCs and patient PBMCs from donors with confirmed diagnoses across 100+ conditions — spanning autoimmune, oncology (cancer), metabolic, neurological, and infectious disease. These are the same peripheral blood mononuclear cells researchers use for biomarker discovery, immune profiling, and drug screening in specific disease contexts. Select a condition from the menu above, or browse common cohorts below.

Need a condition not listed? We run custom disease-state PBMC collections built to your inclusion/exclusion criteria — request a quote.
For related products, see our human leukopak and human whole blood.

Quality and Compliance

  • IRB-approved collections and protocols
  • 21 CFR Part 11-compliant electronic informed consent
  • HIPAA-compliant donor data protection
  • Controlled processing workflows designed to support PBMC quality
  • Documentation available for qualified research programs

Ordering & Shipping

Human PBMC samples are shipped on dry ice and are available in multiple cryopreserved configurations to support a range of research needs. If your project requires custom aliquots, larger bulk orders, or international documentation, our team can help identify the right fulfillment path. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com.

Buy Human PBMCs for Research

Sanguine is a trusted supplier of human PBMCs for research, offering healthy and disease-state PBMC samples from a community of 70,000+ donors. Purchase fresh or cryopreserved patient PBMCs with full donor data, or commission a custom PBMC collection built to your inclusion/exclusion criteria. Browse in-stock PBMC samples above or request a quote to buy PBMCs for your study.

Frequently Asked Questions About Buying PBMCs

How do I buy PBMCs for research?

Browse the in-stock human PBMC samples above or request a quote. Sanguine supplies fresh and cryopreserved PBMCs from healthy and disease-state donors, with custom collections available to your study criteria.

How much do human PBMCs cost?

PBMC pricing depends on cell count, donor type (healthy or disease-state), and fresh vs. cryopreserved format. Request a quote for current PBMC prices and volume discounts on bulk orders.

Do you offer disease-state and patient PBMCs?

Yes. We provide disease-state and patient PBMC samples across 100+ confirmed conditions, plus healthy controls — see the disease-state PBMC list above or request a custom cohort.

Are PBMC samples available for sale fresh and cryopreserved?

Yes. Human PBMC samples are available for purchase in both fresh and cryopreserved formats, in cell counts ranging from 5 million to 2 billion per vial.

Protocols & Documentation

  • PBMC Isolation from Whole Blood

    Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.

    Download

  • Immune Cell Isolation

    Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.

    Download

  • Choosing the Right PBMC Configuration

    Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.

    Download

  • Thawing Cryopreserved PBMC

    Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.

    Download

  • Informed Consent Form (ICF)

    Available upon request — confirms donor consent for research use and downstream commercialization.

PBMC

Frequently Asked Questions

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Are samples IRB approved?

1 Answer

YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.

YES – with the exception of GMP leukopaks, all our products are research use only (RUO).

Our complete catalog can be found here: https://sanguinebio.com/products/

Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.

Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.

Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/

Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.

YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.

Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.

YES – Unique donors can be specified and guaranteed based on your requirements.

For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/

YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.

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Need a custom PBMC cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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