Human PBMC Samples

Human PBMC Samples

About:

Human PBMCs for Research:

Human PBMC samples are collected from healthy and clinically confirmed disease-state donors, then cryopreserved to preserve viability and function. Sanguine’s PBMCs are designed to support a wide range of research applications, from immune profiling and cytokine analysis to cell-based assays and therapeutic development.

In Stock Samples

2,043 samples
Condition
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Country of Collection
2,043 lots available
Healthy PBMC 53709 10990 Female 31-45 Hispanic/Latino Cryopreserved 1 mL 9 30M multi vitamin — United States 2024 A*02:01:01:01/A*25:01:01:01 35:01:01/57:01:01 04:01:01/06:02:01 04:02:01G/08:02:01G 01:01:01G 03:01:01G/04:01:01G 03:02:01G/04:02:01G 01:03:01G/02:01:01G 04:01:01G/05:01:01G
$248
Healthy PBMC 53547 138312 Male 46-60 African American Cryopreserved 1 mL 10 30M — — United States 2024 30:02:01:02/33:03:01:01 — — — — — — — —
$248
Multiple Sclerosis PBMC 70266 129451 Male 46-60 Hispanic/Latino Cryopreserved 1 mL 4 10M Albuterol (Ventolin HFA) 90 mcg- as needed seasonal AllopurinoL (Zyloprim) 300 mg- No longer taking CHOLECAL (IFEROL) - CITAMIN D3 Fluticasone (Flonaze) 50mg Ibprofin (motrin) 200mg Omega 3 Fatty Acids - Fish oil Supplements Tadalafil 20mg ocrevus IV infusions- 2x yr Colchicine 0.6 mg tablets Gout United States 2025 — — — — — — — — —
$530
Multiple Sclerosis PBMC 73941 153790 Female 31-45 Caucasian Cryopreserved 1 mL 10 10M Biotin 1000mg QD Vitamin D QD Propranolol 20mg PRN — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 75571 101223 Female 46-60 Caucasian Cryopreserved 1 mL 10 10M Flexeril 10 mg QD Vit D 10, 000 IU's po QD B-12 QM Zofran PRN Bcomplex QD Klonopin .5 PRN Nurtec 75mg PRN — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 73734 153980 Female 31-45 Caucasian Native American Cryopreserved 1 mL 10 10M Gilenya (fingolimod)- DMT — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 75352 136357 Female 46-60 Caucasian Cryopreserved 1 mL 10 10M Trazadone 150 mg PRN Albuterol PRN Magnesium 500mg QN Metoprolol 25mg ER QD Xanax 0.5 mg qd PRN Flexeral 10mg PRN Vumerity Vitamin D3 2, 000 IC Normethadone Black cohosh supplement menopause — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 74781 96940 Male 31-45 Asian/Pacific Islander Cryopreserved 1 mL 41 50M No medications — United States 2026 A*02:06:01:01/A*24:02:01:01 — — — — — — — —
$1,109
Multiple Sclerosis PBMC 72917 121301 Male 46-60 Caucasian Cryopreserved 1 mL 3 10M Ocrevus 600mg - infusion twice a year Aricept 10mg QD Baclofen 30mg BID Trospium chloride 20mg BID Cymbalta 60mg QD — United States 2026 A*03:01:01:01/A*68:01:02:02 — — — — — — — —
$530
Ulcerative Colitis PBMC 74062 135052 Male 31-45 Caucasian Cryopreserved 1 mL 5 10M Lialda QD, Stelara Q4 weeks — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 74781 96940 Male 31-45 Asian/Pacific Islander Cryopreserved 1 mL 10 10M No medications — United States 2026 A*02:06:01:01/A*24:02:01:01 — — — — — — — —
$530
Ulcerative Colitis PBMC 74070 123680 Male 31-45 Caucasian Cryopreserved 1 mL 2 10M Mesalamine 1.2 mg QID — United States 2026 — — — — — — — — —
$530
Ulcerative Colitis PBMC 74061 90924 Female 61+ Caucasian Cryopreserved 1 mL 4 10M Balsalazide (Colazal) 750mg, 3 per day Levothyroxine/Synthroid 0.100 mcg QD Pantoprazole 40 mg QD — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 73966 130951 Male 46-60 Caucasian Cryopreserved 1 mL 10 10M Levothyroxine 88 mcg once daily Baclofen pump 7.6 mcg an hour or 181.3 mcg a day Ocrevus Advil 200 mg once a night — United States 2026 — — — — — — — — —
$530
Ulcerative Colitis PBMC 74067 111496 Female 18-30 Caucasian Cryopreserved 1 mL 6 10M Nexplanon BC implant — United States 2026 — — — — — — — — —
$530
Multiple Sclerosis PBMC 76047 131643 Female 46-60 Caucasian Cryopreserved 1 mL 10 10M copaxone 30mg injection QD Gabapentin 600mg BID Linzess QD Minocycline QD Prozac Lithium SPRAVATO — United States 2026 — — — — — — — — —
$530
Healthy PBMC 67280 121554 Female 18-30 Caucasian Cryopreserved 1 mL 1 10M Epipen PRN Albuterol inhaler PRN — United States 2025 — — — — — — — — —
$205
Pemphigus PBMC 51442 105959 Female 46-60 Hispanic/Latino Cryopreserved 1 mL 12 10M Omeprazole Vitamin D Rituxan IV treatments — United States 2023 — — — — — — — — —
Healthy PBMC 78119 154884 Female 18-30 Caucasian Cryopreserved 1 mL 6 100M Lexapro 10mg QD Wellbutrin 300mg QD Lamotrigine 100mg QD Amitriptyline 10mg QD Birth Control Pill QD — United States 2026 A*02:01:01:01/A*29:02:01:01 — — — — — — — —
$578
Pemphigus PBMC 47590 130967 Male 46-60 Caucasian Cryopreserved 1 mL 6 10M Cellcept 2000mg BID **Prednisone 4mg (Lowering 1mg per week) Nexium 40mg QD Peroxin 30mg QD Seraquil 500mg QD Ozempic 2mg QW Farxiga 10mg QD Cycloset 2.8mg QD Lipitor 10mg QD Metformin 1000mg BID Toperol XL 25mg QD Vitamin D3 Calcium — United States 2023 — — — — — — — — —
Healthy PBMC 73574 151086 Male 18-30 African American Cryopreserved 1 mL 56 100M No medications — United States 2026 68:02:01:01/74:03:01:01 — — — — — — — —
$578
Pemphigus PBMC 47604 105703 Female 61+ Caucasian Cryopreserved 1 mL 2 10M Rituxan Infusion (8/22, 02/23 next in 08/23) **500mg one time — United States 2023 — — — — — — — — —
Healthy PBMC 74187 154326 Female 18-30 Caucasian Cryopreserved 1 mL 27 100M No medications — United States 2026 02:01:01:01/11:01:01:01 — — — — — — — —
$578
Healthy PBMC 73605 151118 Male 18-30 African American Cryopreserved 1 mL 47 100M No medications — United States 2026 A*02:01:01:01/A*- 52:01:02/53:01:01 01:02:01/16:01:01 03:01:01/09:01:02 01:01:01/not present 03:01:01/05:01:01 02:01:01/not present 02:02:02/03:01:01 01:01:01/04:02:01
$578
Healthy PBMC 69887 139473 Female 18-30 Caucasian Cryopreserved 1 mL 10 100M Adderall 20mg QD Birth Control pill Spironolactone — United States 2025 03:01:01:01/11:01:01:01 — — — — — — — —
$578

Showing 1–25 of 2,043 lots

About Human PBMC Samples

Human PBMC Samples for Research

Human PBMCs are sourced from healthy and disease-state donors and processed under controlled conditions to support high-quality research. These cryopreserved peripheral blood mononuclear cells enable studies in immune function, cytokine response, biomarker discovery, cell therapy research, and therapeutic screening.

Whether you need PBMCs as matched controls, disease-state comparators, or custom donor-defined samples, Sanguine helps research teams source PBMCs aligned to protocol requirements and downstream assay needs.

What Is a PBMC?

Human PBMCs (peripheral blood mononuclear cells) are the round-nucleus immune cells — lymphocytes, monocytes, and dendritic cells — isolated from whole blood or a leukopak, and one of the most widely used starting materials in immunology and cell therapy research. For a full primer, see our guide to human PBMCs.

Product Features

  • Research use only cryopreserved human PBMCs
  • Sourced from healthy and disease-state donors
  • Available in cell counts ranging from 5 million to 2 billion
  • Processed within 24 hours of collection
  • Preserved using CryoStor CS10 freezing media
  • Designed to support cell viability and functional assays
  • IRB-approved protocols and electronic informed consent
  • Screening and bulk-order support available for larger PBMC programs

De-identified Donor Data

Available donor-level information helps researchers select PBMC samples that align to study design and population requirements.

  • Donor demographics including age, sex assigned at birth, and race/ethnicity
  • Self-reported allergies and infectious disease history
  • Healthy donor and disease-state context where applicable
  • Additional donor-specific data available upon request
  • Study-specific donor requirements may be supported for custom programs

Applications

Human PBMCs support a broad range of immunology and translational research workflows.

  • Biomarker discovery and validation
  • Drug screening and therapeutic development
  • Immune pathway analysis
  • Cytokine and functional immune assays
  • Transcriptomic and proteomic profiling
  • Cell-based assay development
  • Matched control and disease-state comparison studies

Disease-State & Patient PBMCs

Sanguine supplies disease-state PBMCs and patient PBMCs from donors with confirmed diagnoses across 100+ conditions — spanning autoimmune, oncology (cancer), metabolic, neurological, and infectious disease. These are the same peripheral blood mononuclear cells researchers use for biomarker discovery, immune profiling, and drug screening in specific disease contexts. Select a condition from the menu above, or browse common cohorts below.

Need a condition not listed? We run custom disease-state PBMC collections built to your inclusion/exclusion criteria — request a quote.

For related products, see our human leukopak and human whole blood.

Quality and Compliance

  • IRB-approved collections and protocols
  • 21 CFR Part 11-compliant electronic informed consent
  • HIPAA-compliant donor data protection
  • Controlled processing workflows designed to support PBMC quality
  • Documentation available for qualified research programs

Ordering & Shipping

Human PBMC samples are shipped on dry ice and are available in multiple cryopreserved configurations to support a range of research needs. If your project requires custom aliquots, larger bulk orders, or international documentation, our team can help identify the right fulfillment path. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com.

Buy Human PBMCs for Research

Sanguine is a trusted supplier of human PBMCs for research, offering healthy and disease-state PBMC samples from a community of 70,000+ donors. Purchase fresh or cryopreserved patient PBMCs with full donor data, or commission a custom PBMC collection built to your inclusion/exclusion criteria. Browse in-stock PBMC samples above or request a quote to buy PBMCs for your study.

Frequently Asked Questions About Buying PBMCs

How do I buy PBMCs for research?

Browse the in-stock human PBMC samples above or request a quote. Sanguine supplies fresh and cryopreserved PBMCs from healthy and disease-state donors, with custom collections available to your study criteria.

How much do human PBMCs cost?

PBMC pricing depends on cell count, donor type (healthy or disease-state), and fresh vs. cryopreserved format. Request a quote for current PBMC prices and volume discounts on bulk orders.

Do you offer disease-state and patient PBMCs?

Yes. We provide disease-state and patient PBMC samples across 100+ confirmed conditions, plus healthy controls — see the disease-state PBMC list above or request a custom cohort.

Are PBMC samples available for sale fresh and cryopreserved?

Yes. Human PBMC samples are available for purchase in both fresh and cryopreserved formats, in cell counts ranging from 5 million to 2 billion per vial.

Donor Metadata

  • Verified diagnosis and clinical history
  • Demographic data: age, sex assigned at birth, race/ethnicity
  • Medication and treatment background when available

Compliance and Quality Assurance

  • IRB-approved collections and standardized procedures
  • 21 CFR Part 11-compliant e-consent system
  • HIPAA-compliant data management

Ordering & Customization

Human PBMC are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.

Protocols & Documentation

  • PBMC Isolation from Whole Blood

    Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.

    Download

  • Immune Cell Isolation

    Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.

    Download

  • Choosing the Right PBMC Configuration

    Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.

    Download

  • Thawing Cryopreserved PBMC

    Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.

    Download

  • Informed Consent Form (ICF)

    Available upon request — confirms donor consent for research use and downstream commercialization.

PBMC

Where can I find your complete catalog?

You can find our full product catalog here.

How long can samples be stored?

Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.

What customization options are available?

Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.

Do you offer prospective collections?

Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.

What is the turnaround time for custom collections?

Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.

Do you have samples in stock?

YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.

What does unique donor mean?

Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.

Are samples collected under IRB-approved protocols?

YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.

Frequently Asked Questions

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Need a custom PBMC cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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