Healthy CD34+ Cord Blood Cells
About:Healthy CD34+ Cord Blood Cells are isolated from the umbilical cord blood of consented healthy donors. These multipotent hematopoietic stem and progenitor cells (HSPCs) are ideal for studies in hematopoiesis, cell and gene therapy development, and the creation of humanized mouse models.
About Healthy CD34+ Cord Blood Cells
Healthy CD34+ Cord Blood Cells
High-purity human CD34+ hematopoietic stem and progenitor cells (HSPCs) isolated from umbilical cord blood.
Human CD34+ cells are purified from umbilical cord blood sourced from healthy, full-term deliveries under strict protocols. As the primary marker for primitive hematopoietic stem cells, CD34+ cells possess the unique ability to self-renew and differentiate into all lineages of the blood and immune system, including myeloid and lymphoid cells.
Compared to adult bone marrow-derived stem cells, cord blood-derived CD34+ cells are considered more “naive,” offering higher proliferative potential and greater expansion capacity in vitro. They also carry a lower mutational burden than adult sources and are collected without any risk or procedure burden to a donor. These cells are essential for researchers investigating stem cell biology, hematopoietic reconstitution, and the development of next-generation cell therapies. Available cryopreserved in specialized media, these cells ensure high post-thaw viability and immediate readiness for downstream assays.
Choosing Between CD34+ Sources
The right CD34+ source depends on what you are modelling:
- Cord blood CD34+ — most primitive phenotype, highest expansion potential, best for long-term engraftment and hematopoiesis studies
- Mobilized peripheral blood CD34+ — higher yield per collection, adult genetic background; see our healthy mobilized CD34+ cells
- Whole cord blood units — if you want to isolate CD34+ yourself alongside other fractions, see healthy cord blood
Product Features
- Research Use Only (RUO) CD34+ hematopoietic stem and progenitor cells
- Isolated from healthy donors with full IRB consent and documented protocols
- Cryopreserved in CryoStor® CS10 media
- Greater than 90% viability and purity
- Processed within 24 hours of collection
- Custom CD34+ cell doses and aliquot sizes available on request
Specifications
- Flow cytometry CD34+ purity and post-thaw viability data supplied per lot
- Total viable CD34+ cell count per vial confirmed before release
- Isolated by immunomagnetic positive selection
- Colony-forming unit (CFU) potential data available on request
Donor Metadata
- Demographic data: age, sex assigned at birth, race/ethnicity
- Infectious disease testing results
- Blood type when available
- HLA type available on request
Applications
- Hematopoiesis Studies: Investigating the differentiation pathways of myeloid and lymphoid lineages.
- Cell & Gene Therapy: Serving as a cellular substrate for CRISPR/Cas9 editing and viral vector transduction.
- Humanized Mouse Models: Supporting long-term engraftment in immunodeficient strains (e.g. NSG mice).
- Drug Discovery: Toxicity screening and efficacy testing for hematological drug candidates.
- Expansion Assays: Evaluating the impact of cytokines and small molecules on stem cell self-renewal.
- Sickle cell and thalassemia gene-correction research.
Compliance and Quality Assurance
- Collected from consented donors at FDA-compliant clinical sites following established regulatory and ethical standards
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Frequently Asked Questions
How many CD34+ cells are in a vial? Vial contents are specified per lot and custom doses can be prepared. Tell us the CD34+ cell number your protocol requires and we will confirm availability.
Are the cells suitable for humanized mouse engraftment? Yes — cord blood CD34+ cells are widely used for engraftment in immunodeficient strains such as NSG. HLA typing is available where donor matching matters.
Can I get matched plasma or other fractions from the same donation? Yes, where the collection volume allows. Whole units are also available if you prefer to isolate fractions yourself.
Ordering & Customization
Healthy CD34+ Cord Blood Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. For related starting material, see our human PBMCs and human leukopak collections.
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD34+ Cord Blood Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
Ask a Question
Need a custom CD34+ Cord Blood Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.