Leukopak

Human Leukopak for Immunology Research

Human leukopak samples are collected from IRB-consented donors through IRB-approved apheresis procedures. Each human leukopak contains large quantities of peripheral blood mononuclear cells (PBMCs), supporting immune profiling, cytokine analysis, translational research, and cell therapy research applications. Fresh and cryopreserved leukopaks are available for sale, with pricing and current stock on request.

What Is Leukapheresis?

Leukapheresis is an apheresis procedure that separates and collects white blood cells (leukocytes) from a donor’s peripheral blood while returning red blood cells, platelets, and plasma to the donor. The concentrated white-cell product — a leukopak — yields far more peripheral blood mononuclear cells (PBMCs) than a standard blood draw, which is why leukopaks are the preferred starting material for immunology, immuno-oncology, and cell and gene therapy research. Sanguine collects each leukopak by leukapheresis under IRB-approved protocols from consented healthy and disease-state donors. Learn more in our guide: What Is Leukapheresis?

Leukopak Specifications: Volume, Cell Count, and Composition

A frequent question is simply how many cells a leukopak contains. Yields vary by donor and collection parameters, so every leukopak ships with its own measured values rather than a nominal figure:

Total nucleated cells (TNC) — reported per collection; a full leukopak typically delivers cell numbers an order of magnitude above a standard venipuncture draw

Volume — full and half leukopak formats available; target volume specified to your protocol

Composition — predominantly mononuclear cells: T cells, B cells, NK cells, and monocytes, with variable granulocyte and platelet carryover depending on collection settings

Anticoagulant — ACD-A standard; alternatives on request

Viability — measured and reported, with post-thaw viability supplied for cryopreserved units

Certificate of Analysis available for every collection

Tell us the PBMC number your protocol requires and we will confirm whether a half or full leukopak — or a scheduled series — is the right fit.

Fresh vs Cryopreserved Leukopaks

Both formats are available, and the choice is usually driven by assay sensitivity versus scheduling flexibility:

Fresh leukopak — shipped temperature-controlled within 24 hours of collection. Preferred for functional assays, granulocyte work, and any application where cryopreservation artefacts are a concern. Requires you to process on arrival, so collection slots are reserved in advance.

Cryopreserved leukopak — banked and shipped on dry ice. Preferred for flexible scheduling, batched experiments, and multi-site studies where all arms need identical material.

Downstream Isolation From a Leukopak

Most customers isolate specific populations after receipt. A single leukopak commonly supports parallel isolation of:

1. CD3+ pan-T cells, CD4+ and CD8+ T cells
2. CD19+ B cells and CD56+ NK cells
3. Monocytes and monocyte-derived dendritic cells
4. Mobilized collections for CD34+ hematopoietic stem cells

If you would rather receive the isolated fraction than perform the separation yourself, we can isolate to your specification before shipment.

Product Features

• Human leukopak samples for Research Use Only (RUO)
• Human leukopak samples collected from healthy and disease-state donors
• High cell yield suitable for large-scale and longitudinal studies
• Fresh leukopak processing and shipment within 24 hours of collection
• Fresh and cryopreserved human leukopak samples available
• Full and half leukopak formats
• IRB-approved and ethically sourced
• Infectious disease testing performed
• HLA-A typing available
• Donors screened using LeukoLot™

Donor Metadata

• Donor demographics: age, sex assigned at birth, race/ethnicity
• Physician- or specialist-confirmed diagnosis (healthy or disease-state)
• Self-reported medication history, comorbidities, and allergies
• CMV serostatus and HLA type available on request
• Repeat collections from the same qualified donor where available

Applications

• Immune cell characterization in healthy and disease-state cohorts
• CAR-T, CAR-NK, and engineered cell therapy process development
• Therapeutic development and screening
• Cell-based assays and cytokine profiling
• Multi-omics studies, including single-cell sequencing

Disease-State Leukopak Samples

Sanguine collects leukopaks from donors with confirmed diagnoses across a range of conditions, including:

• Rheumatoid Arthritis Leukopak
• Relapsing-Remitting Multiple Sclerosis Leukopak
• Secondary Progressive Multiple Sclerosis Leukopak
• Stroke Leukopak
• Solid Tumor Cancer Leukopak
• Skin Cancer Leukopak

For smaller cell needs, see our human PBMCs.

Human Leukopak for Cell Therapy Research

Buy human leukopak samples for immunology, translational, and cell therapy research with custom donor criteria, documentation support, and flexible collection options.

Compliance and Quality Assurance

• Collected under IRB oversight with donor e-consent (21 CFR Part 11 compliant)
• HIPAA-compliant handling of donor information
• Rigorous donor screening, traceability, and documentation

Ordering & Customization

Purchase human leukopak samples in fresh or cryopreserved formats to support diverse research applications. If you need to buy leukopak for research with specific donor criteria, Sanguine can support custom collection and fulfillment. For international shipping or regulatory documentation, please contact learnmore@sanguinebio.com to confirm regional compliance and availability.

Frequently Asked Questions About Buying Leukopaks

How much does a leukopak cost?

Leukopak pricing depends on cell yield, fresh vs. cryopreserved format, donor criteria, and disease state. Request a quote for current leukopak pricing and volume options.

How many cells are in a leukopak?

Total nucleated cell count varies by donor and collection parameters, and every leukopak is supplied with its own measured TNC and viability values. A full leukopak yields substantially more PBMCs than a standard blood draw — tell us your target cell number and we will confirm what is achievable.

What is in a leukopak?

A leukopak is a concentrated leukocyte product, predominantly mononuclear cells — T cells, B cells, NK cells, and monocytes — with variable granulocyte and platelet carryover depending on collection settings.

Can I buy fresh and cryopreserved leukopaks?

Yes — fresh and cryopreserved human leukopaks are available for sale, with same-day fresh collection and reservable slots.

Can I order a half leukopak?

Yes. Half and full formats are both available, which is often the more economical choice for smaller studies.

Do you offer custom and disease-state leukopak collections?

Yes — purchase leukopaks from healthy or disease-state donors, or commission a custom leukopak collection built to your inclusion/exclusion criteria.

Do you offer leukopak collection services and scheduled draws?

Yes. Recurring and scheduled leukopak collection programmes can be arranged, including repeat draws from the same qualified donor for longitudinal work.