Leukopak
Powered by BiozAbout:Human Leukopak Samples for Research, source fresh or cryopreserved human leukopak samples from healthy and disease-state donors for immunology, translational, and cell therapy research.
About Leukopak
Human Leukopak for Immunology Research
Human leukopak samples are collected from IRB-consented donors through IRB-approved apheresis procedures. Each human leukopak contains large quantities of peripheral blood mononuclear cells (PBMCs), supporting immune profiling, cytokine analysis, translational research, and cell therapy research applications. Fresh and cryopreserved leukopaks are available for sale, with pricing and current stock on request.
What Is Leukapheresis?
Leukapheresis is an apheresis procedure that separates and collects white blood cells (leukocytes) from a donor’s peripheral blood while returning red blood cells, platelets, and plasma to the donor. The concentrated white-cell product — a leukopak — yields far more peripheral blood mononuclear cells (PBMCs) than a standard blood draw, which is why leukopaks are the preferred starting material for immunology, immuno-oncology, and cell and gene therapy research. Sanguine collects each leukopak by leukapheresis under IRB-approved protocols from consented healthy and disease-state donors. Learn more in our guide: What Is Leukapheresis?
Leukopak Specifications: Volume, Cell Count, and Composition
A frequent question is simply how many cells a leukopak contains. Yields vary by donor and collection parameters, so every leukopak ships with its own measured values rather than a nominal figure:
Total nucleated cells (TNC) — reported per collection; a full leukopak typically delivers cell numbers an order of magnitude above a standard venipuncture draw
Volume — full and half leukopak formats available; target volume specified to your protocol
Composition — predominantly mononuclear cells: T cells, B cells, NK cells, and monocytes, with variable granulocyte and platelet carryover depending on collection settings
Anticoagulant — ACD-A standard; alternatives on request
Viability — measured and reported, with post-thaw viability supplied for cryopreserved units
Certificate of Analysis available for every collection
Tell us the PBMC number your protocol requires and we will confirm whether a half or full leukopak — or a scheduled series — is the right fit.
Fresh vs Cryopreserved Leukopaks
Both formats are available, and the choice is usually driven by assay sensitivity versus scheduling flexibility:
Fresh leukopak — shipped temperature-controlled within 24 hours of collection. Preferred for functional assays, granulocyte work, and any application where cryopreservation artefacts are a concern. Requires you to process on arrival, so collection slots are reserved in advance.
Cryopreserved leukopak — banked and shipped on dry ice. Preferred for flexible scheduling, batched experiments, and multi-site studies where all arms need identical material.
Downstream Isolation From a Leukopak
Most customers isolate specific populations after receipt. A single leukopak commonly supports parallel isolation of:
- CD3+ pan-T cells, CD4+ and CD8+ T cells
- CD19+ B cells and CD56+ NK cells
- Monocytes and monocyte-derived dendritic cells
- Mobilized collections for CD34+ hematopoietic stem cells
If you would rather receive the isolated fraction than perform the separation yourself, we can isolate to your specification before shipment.
Product Features
- Human leukopak samples for Research Use Only (RUO)
- Human leukopak samples collected from healthy and disease-state donors
- High cell yield suitable for large-scale and longitudinal studies
- Fresh leukopak processing and shipment within 24 hours of collection
- Fresh and cryopreserved human leukopak samples available
- Full and half leukopak formats
- IRB-approved and ethically sourced
- Infectious disease testing performed
- HLA-A typing available
- Donors screened using LeukoLot™
Donor Metadata
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Physician- or specialist-confirmed diagnosis (healthy or disease-state)
- Self-reported medication history, comorbidities, and allergies
- CMV serostatus and HLA type available on request
- Repeat collections from the same qualified donor where available
Applications
- Immune cell characterization in healthy and disease-state cohorts
- CAR-T, CAR-NK, and engineered cell therapy process development
- Therapeutic development and screening
- Cell-based assays and cytokine profiling
- Multi-omics studies, including single-cell sequencing
Disease-State Leukopak Samples
Sanguine collects leukopaks from donors with confirmed diagnoses across a range of conditions, including:
- Rheumatoid Arthritis Leukopak
- Relapsing-Remitting Multiple Sclerosis Leukopak
- Secondary Progressive Multiple Sclerosis Leukopak
- Stroke Leukopak
- Solid Tumor Cancer Leukopak
- Skin Cancer Leukopak
For smaller cell needs, see our human PBMCs.
Human Leukopak for Cell Therapy Research
Buy human leukopak samples for immunology, translational, and cell therapy research with custom donor criteria, documentation support, and flexible collection options.
Compliance and Quality Assurance
- Collected under IRB oversight with donor e-consent (21 CFR Part 11 compliant)
- HIPAA-compliant handling of donor information
- Rigorous donor screening, traceability, and documentation
Ordering & Customization
Purchase human leukopak samples in fresh or cryopreserved formats to support diverse research applications. If you need to buy leukopak for research with specific donor criteria, Sanguine can support custom collection and fulfillment. For international shipping or regulatory documentation, please contact learnmore@sanguinebio.com to confirm regional compliance and availability.
Frequently Asked Questions About Buying Leukopaks
How much does a leukopak cost?
Leukopak pricing depends on cell yield, fresh vs. cryopreserved format, donor criteria, and disease state. Request a quote for current leukopak pricing and volume options.
How many cells are in a leukopak?
Total nucleated cell count varies by donor and collection parameters, and every leukopak is supplied with its own measured TNC and viability values. A full leukopak yields substantially more PBMCs than a standard blood draw — tell us your target cell number and we will confirm what is achievable.
What is in a leukopak?
A leukopak is a concentrated leukocyte product, predominantly mononuclear cells — T cells, B cells, NK cells, and monocytes — with variable granulocyte and platelet carryover depending on collection settings.
Can I buy fresh and cryopreserved leukopaks?
Yes — fresh and cryopreserved human leukopaks are available for sale, with same-day fresh collection and reservable slots.
Can I order a half leukopak?
Yes. Half and full formats are both available, which is often the more economical choice for smaller studies.
Do you offer custom and disease-state leukopak collections?
Yes — purchase leukopaks from healthy or disease-state donors, or commission a custom leukopak collection built to your inclusion/exclusion criteria.
Do you offer leukopak collection services and scheduled draws?
Yes. Recurring and scheduled leukopak collection programmes can be arranged, including repeat draws from the same qualified donor for longitudinal work.
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human Leukopak are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Protocols & Documentation
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Leukopak Cryopreservation
Standard operating procedure for cryopreserving leukopak units with controlled freezing and post-thaw viability targets.
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Leukopak Thawing
Validated thawing workflow for cryopreserved leukopaks to maximize recovery while maintaining sterility and chain of custody.
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Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
Leukopak
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Need a custom Leukopak cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.