Synovial Fluid
About: Human synovial fluid samples support research into joint inflammation, immune signaling, biomarker discovery, and disease-specific mechanisms. Whether you need in-stock synovial fluid specimens or a custom prospective collection program, Sanguine helps research teams source synovial fluid aligned to their protocol, donor criteria, and study timeline.
| Lot Number | Condition | Race/Ethnicity | Age | Gender | Country of Collection | Medications | Vials | Price | Action |
|---|---|---|---|---|---|---|---|---|---|
| 76954 | Rheumatoid Arthritis | Hispanic/Latino | 78 | Female | 1 | ||||
| 76376 | Osteoarthritis | African American | 56 | Female |
Benlysta Injection once week Hydroxychloroquine 200mg qd Methotrexate 25mg Mondays Folic Acid Stopped Lisinopril 2 weeks ago and now taking hydrochlorothiazide 25 qd Gabapentin 300mg qd Vitamin D3 200mg qd Zyrtec Inhaler Fluticasone 50mcg bid
|
1 | |||
| 76378 | Osteoarthritis | Caucasian African American | 42 | Male |
Cymbalta 60mg 1x a day gabapentin- 300mg a day
|
17 | |||
| 76382 | Osteoarthritis | Caucasian | 67 | Male |
Losartan Rinvoq // 30 mg // QD
|
3 | |||
| 76723 | Rheumatoid Arthritis | Male |
Arcoxia
|
1 | |||||
| 76721 | Rheumatoid Arthritis | Male |
Arcoxia
|
1 | |||||
| 76704 | Rheumatoid Arthritis | Male |
Diclofenac, Etoricoxib
|
1 | |||||
| 76703 | Rheumatoid Arthritis | Male |
Diclofenac, Etoricoxib
|
1 | |||||
| 76678 | Rheumatoid Arthritis | Female |
Diclofenac sodium
|
1 | |||||
| 76677 | Rheumatoid Arthritis | Female |
Diclofenac sodium
|
1 |
Human Synovial Fluid Samples for Research
Human synovial fluid samples are collected from clinically confirmed donors and support a wide range of inflammation, autoimmune, rheumatology, and translational research applications. Sanguine provides research-use-only synovial fluid specimens with flexible sourcing options for healthy and disease-state donor programs.
These high-quality synovial fluid samples can support studies focused on cytokine activity, immune-cell profiling, biomarker discovery, proteomic analysis, and therapeutic response. Whether your team needs retrospective inventory or custom prospective collection, we work with you to align specimen sourcing to your research objectives.
What Is Synovial Fluid?
Synovial fluid is the viscous, clear-to-pale-yellow fluid found in the cavities of synovial joints such as the knee, hip, and shoulder. Rich in hyaluronic acid and lubricin, it lubricates the joint, reduces friction between articular cartilage surfaces, and delivers nutrients to cartilage. Because its cellular and biochemical composition changes measurably in arthritis and autoimmune joint disease, synovial fluid is a valuable specimen for studying inflammation, cartilage degradation, and joint pathology.
Product Features
- Research use only synovial fluid samples in fresh or frozen formats
- Collected from clinically characterized donors
- Available for healthy and disease-state research programs
- Collected by licensed clinicians under aseptic conditions
- Frozen within 4 hours of collection when requested
- Processed and shipped same-day where applicable
- IRB-approved protocols and electronic informed consent
- Custom sourcing support available for disease-specific studies
De-identified Donor Data
Available donor-level data helps researchers contextualize each synovial fluid specimen for downstream analysis.
- Verified diagnosis where applicable
- Donor demographics including age, sex assigned at birth, and race/ethnicity
- Self-reported medication history
- Affected joint information where available
- Disease activity and clinical history available upon request
- Additional study-specific data may be available depending on program design
Applications
Human synovial fluid samples can support a broad range of research workflows and analytical applications.
- Cytokine and inflammatory signaling analysis
- Cellular and immune profiling of synovial fluid
- Transcriptomic and proteomic analysis
- Biomarker discovery and immunophenotyping
- Therapeutic response and drug target validation
- Autoimmune and rheumatology research
- Joint disease mechanism studies
Disease-State Synovial Fluid Samples
Sanguine offers synovial fluid from donors with a range of confirmed joint and autoimmune conditions:
- Rheumatoid Arthritis Synovial Fluid
- Osteoarthritis Synovial Fluid
- Gout Synovial Fluid
- Psoriatic Arthritis Synovial Fluid
- Ankylosing Spondylitis Synovial Fluid
- Systemic Lupus Erythematosus Synovial Fluid
- Sjogren’s Syndrome Synovial Fluid
- Vasculitis Synovial Fluid
- Arthritis Synovial Fluid
- Axial Spondyloarthritis Synovial Fluid
Quality and Compliance
- IRB-approved collections and SOP-driven processing workflows
- 21 CFR Part 11-compliant electronic informed consent
- HIPAA-compliant donor data management
- Quality-focused handling designed to preserve specimen integrity
- Documentation available upon request for qualified research programs
Ordering & Shipping
Human synovial fluid samples can be shipped ambient, refrigerated, or on dry ice depending on specimen format and study requirements. If your program involves custom sourcing, special handling, or international documentation needs, our team can help define the best fulfillment approach for your research. To learn more about the biology, read our overview of synovial fluid and its role in joint health.
For international orders or regulatory documentation, please contact learnmore@sanguinebio.com.
Frequently Asked Questions
1 Answer
YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
1 Answer
YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
1 Answer
Our complete catalog can be found here: https://sanguinebio.com/products/
1 Answer
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
1 Answer
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
1 Answer
Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
1 Answer
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
1 Answer
YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
1 Answer
Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
1 Answer
YES – Unique donors can be specified and guaranteed based on your requirements.
1 Answer
For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
1 Answer
YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom Synovial Fluid cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.