Primary Biliary Cholangitis PBMC
About: Primary Biliary Cholangitis PBMC samples are collected from clinically confirmed Primary Biliary Cholangitis (PBC) donors and cryopreserved. These PBMCs are ideal for investigating T cell response, B cell activity, and cytokine production.
| Lot Number | Condition | Cell Count (M) | Race/Ethnicity | Age | Gender | Country of Collection | Medications | Vials | Price | Action |
|---|---|---|---|---|---|---|---|---|---|---|
| 73455 | Primary Biliary Cholangitis (Cirrhosis) | 10M | Hispanic/Latino | 44 | Female |
Ursodiol/500mg/TID Omeprazole/20mg/QD Zyrtec/10mg/QD Albuterol/PRN
|
2 | |||
| 73540 | Primary Biliary Cholangitis (Cirrhosis) | 10M | Caucasian | 56 | Female |
Ursodiol 1250mg total Ocaliva 10mg po qd Atorvastatin 40mg po qd Levothyroxine 150mcg po qd Pantoprozole 40mg po qd Rifampin 150mg po bid Calcium citrate 1200mg po qd
|
2 | |||
| 73724 | Primary Biliary Cholangitis (Cirrhosis) | 10M | Caucasian | 74 | Male | United States (US) |
Crestor 10mg po qd Lipitor 10mg po qd Metformin 500mg po bid Vit D 500IU po qd Ursodiol 500mg AM --> 250mg lunch -->500mg PM QD Ozempic injectable qweekly medical marijuana vaping out of cartridge
|
8 | ||
| 73690 | Primary Biliary Cholangitis (Cirrhosis) | 10M | Caucasian | 75 | Female | United States (US) |
Ursodiol 250 mg TID NOT on Ocaliva Topical ointment-Triamcinolone Acetonide 0.1% applied daily-pea sized amount.
|
3 | ||
| 73420 | Primary Biliary Cholangitis (Cirrhosis) | 10M | Caucasian | 63 | Female | United States (US) |
lisinopril 10 mg QD cytamil for throid 5 mcg BID np (armoer thyroid) 60 mg QD omeprazole 40 mg QD baby aspirin ursodiol 250 mg x2 BID
|
2 | ||
| 55916 | Primary Biliary Cholangitis (Cirrhosis) | 5M | Caucasian | 74 | Male | United States (US) |
Crestor 10mg po qd Lipitor 10mg po qd Metformin 500mg po bid Vit D 500IU po qd Ursodiol 500mg AM --> 250mg lunch -->500mg PM QD Ozempic injectable qweekly
|
6 | $891.00 | |
| 55896 | Primary Biliary Cholangitis (Cirrhosis) | 5M | Caucasian Hispanic/Latino | 44 | Female | United States (US) |
Ursodiol 600mg BID Carosate 1mg 4/day lemotrogen 200mg QD Wellbutrin 100mg BID prylosec 20mg QD Adidrax 25mg every 6 hours Bentyl 20mg QD
|
6 | $891.00 |
Primary Biliary Cholangitis PBMC for Research
Primary Biliary Cholangitis Human PBMC products are sourced from donors clinically diagnosed with Primary Biliary Cholangitis (PBC) and processed under stringent conditions to support research. These cryopreserved peripheral blood mononuclear cells (PBMCs) enable studies related to autoimmune liver damage including T cell response, B cell activity, and cytokine production.
Product Features
- Research Use Only (RUO), cryopreserved PBMCs
- Clinically confirmed PBC donors
- Available in cell counts ranging from 5 million to 2 billion
- Processed within 24 hours of collection
- Stored using CryoStor® CS10 freezing media
- IRB-approved protocols and electronic informed consent
- Screen LeukoLot™ available prior to bulk orders
De-identified Donor Data
- Verified PBC diagnosis
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Self-reported allergies and infectious disease history
- Additional PBC-specific data available upon request
Applications
- Biomarker discovery and validation
- Drug screening and therapeutic development
- Immune pathway analysis in Primary Biliary Cholangitis (PBC) pathophysiology
- Transcriptomic and proteomic profiling
Quality and Compliance
- IRB-approved collections and protocols
- 21 CFR Part 11 – compliant e-consent system
- HIPAA-compliant donor data protection
Ordering & Shipping
Primary Biliary Cholangitis PBMC samples are shipped on dry ice and available in custom aliquots. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com to confirm documentation and compliance needs.
Protocols & Documentation
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Download
PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Download
Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Download
Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Download
Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
1 Answer
YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
1 Answer
YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
1 Answer
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
1 Answer
Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
1 Answer
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
1 Answer
YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.