Hypertension PBMC
About: Hypertension PBMC samples are isolated from donors with clinically diagnosed hypertension. Ideal for studying immune cell involvement in vascular inflammation, endothelial dysfunction, and chronic cardiovascular stress.
Hypertension PBMC for Research
Hypertension PBMC samples are collected from donors clinically diagnosed with hypertension (high blood pressure) and processed under controlled conditions to support cardiovascular and immunology research. These cryopreserved peripheral blood mononuclear cells (PBMCs) enable studies of immune-cell involvement in vascular inflammation, endothelial dysfunction, and chronic cardiovascular stress.
Product Features
- Research Use Only (RUO), cryopreserved hypertension PBMC samples
- Clinically confirmed hypertension donors
- Available in cell counts ranging from 5 million to 2 billion
- Processed within 24 hours of collection
- Preserved using CryoStor® CS10 freezing media
- IRB-approved protocols and electronic informed consent
- Screening (LeukoLot™) available prior to bulk orders
De-identified Donor Data
- Verified hypertension diagnosis
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Self-reported allergies and infectious disease history
- Additional hypertension-specific clinical data available on request
Applications
- Biomarker discovery and validation
- Immune-pathway and vascular-inflammation analysis in hypertension
- Drug screening and therapeutic development
- Transcriptomic and proteomic profiling
Quality and Compliance
- IRB-approved collections and protocols
- 21 CFR Part 11-compliant e-consent
- HIPAA-compliant donor data protection
Ordering & Shipping
Hypertension PBMC samples ship on dry ice in standard or custom aliquots. For international orders or regulatory documentation, contact learnmore@sanguinebio.com. Browse all human PBMCs or request a custom disease-state collection.
Protocols & Documentation
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PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
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Electronic medical records are an option to be included with the PBMC sample, as well as, flow cytometry and other phenotypic testing.
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YES – we can often accommodate treatment-naive samples including various cancers, and you can specify immunosupression status or other requirements in the I/E criteria.
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Self-reported infectious disease testing is always available and some of our products have additional testing.
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HLA-typing is available for some of our PBMC products.
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YES to both – Unique donors can be specified, and multiple vials from the same donor can be arranged. You can specify these requirements when ordering.
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Healthy PBMCs achieve over 90% vialbity post-thaw. Although our disease-state PBMCs are processed with same stringent SOP, there is more variability depending upon disease. Learn more about our post thaw viability here. https://sanguinebio.com/pbmc-viability-quality-assurance/
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Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.