Scleroderma PBMC
About: Scleroderma PBMC samples are collected from clinically confirmed scleroderma (systemic sclerosis) donors and cryopreserved. These PBMCs are ideal for investigating immune cell phenotypes, cytokine production, and gene expression.
| Lot Number | Condition | Cell Count (M) | Race/Ethnicity | Age | Gender | Country of Collection | Medications | Vials | Price | Action |
|---|---|---|---|---|---|---|---|---|---|---|
| 74801 | Scleroderma | 10M | Caucasian | 61 | Female |
Current: cellcept mycophenolate 2500mg QD nifedipine 30mg QD Multivitamin Previous: omeprazole 20 mg
|
4 | |||
| 74166 | Scleroderma | 10M | Hispanic/Latino | 31 | Female |
imuran 50 mg QD Tacrolimus 1mg 2 tab QD aygestin 10 mg QD Nutrofol QD Multivitamin
|
3 | |||
| 65255 | Scleroderma | 34M | Caucasian | 58 | Female |
Current Meds: cellcept 500mg QD Opsumit 10 mg QD Tadalafil 10mg QD spironolactone 40mg QD furosemide 40 mg QD Cutaquig (IVIG) 50mcg (twice per month, last one approx 3/26/25) Rabecrazole 20mg QD Jardiance 10mg QD Zep bound injection 7mg liothyronine 5mcg QD Levothyroxine 100mcg QD Previous Meds: np thyroid 90 mg QD mycophenolate 1000 mg BID prednisone 8 mg QD Adempas1 mg TID Hizentra 50 ml QW infusion Xiidra eye drops QD Flonase QD DHEA 15 mg QD Pregnanolone 30 mg QD Multivitamin QD Vitamin C 125 mcg QD Probiotic QD Magnesium 400 mg QD Omega 3 950 mg QD Folate QD B12 QD
|
2 | |||
| 74793 | Scleroderma | 10M | African American | 45 | Female | United States (US) |
allopurinol // 300 mg // QD Cellcept 3 tablets in AM and PM// 500mg // BID Colchicine // 0.6 mg // prn bumex // 2mg // QD verapamil // 60 mg // BID Plaquenil // 200 mg // QD adempas // 2.5 mg // TID cymbalta // 60 mg // BID Protonix // 40mg // BID captopril // 50mg // TID micronor // 0.35 mg // QD calcitral 0.25 mg QD protonics 40mgs BID potassium supplement 10mcq PRN Bumax 2mg 3 times per week Spironolactone 25mg BID
|
2 | ||
| 74254 | Scleroderma | 10M | African American | 49 | Male | United States (US) |
Mycophenolic acid 500mg 3 tablets BID Omeprazole 40mg QD Ibuterol PRN
|
6 | ||
| 73148 | Scleroderma | 10M | Caucasian | 60 | Female | United States (US) |
Omeprazole 20mg BID Rosuvastatin 5mg QD Nebivolol 5mg QD (2.5am, 2.5pm) Baby Aspirin 81mg QD Vitamin D 5000iu QD Duloxetine 60 mg QD Zepbound Inj QW
|
4 | ||
| 73118 | Scleroderma | 10M | Caucasian | 64 | Female | United States (US) |
Amlodipine 5mg QD Azelastine 137mcg BID Ciclopirox 8% solution Topically QN Dexlansoprazole 60mg BID Levothyroxine 125mcg QD Linzess 290mcg QD Losartan 25mg QD Myrbetriq 50mg QD Pilocarpine 5mg TID
|
7 | ||
| 70872 | Scleroderma | 50M | Hispanic/Latino | 61 | Female | United States (US) |
Mycophenolate 500mg BID Nifedipine 30mg QD Cymbalta 60mg QD Omeprazole 40mg QD Atorvastatin 80mh QD Valacyclovir 500mg QD
|
4 | ||
| 70405 | Scleroderma | 10M | Caucasian | 54 | Female | United States (US) |
Nifedipine/60mg/QD - extended release Plaquenil/200mg/BID Metoprolol Tartrate/12.5mg/QD Atorvastatin/80mg/QD Wellbutrin/150mg/QD Triamcinolone/1%/PRN Ambien/10mg/QPM Lasix/40mg/BID Acetyloprine/10mg/QD Mycophenolate mofentil/500mg*2/BID Aspirin/81mg/BIW Multivitamin/QD Hair skin and nails supplement/QD Methotrexate Cyclovir CBD gummy no THC as needed
|
5 | ||
| 65554 | Scleroderma | African American | 46 | Female | United States (US) |
Nexium 40mg BID Plaquenil 200mg BID Terazosin 1mg QD Pentoxifylline 400mg BID Symbicort Inhaler 2 puffs BID Asthma inhaler as needed Cellcept 500mg BID Pentoxifylline 400mg BID Ibuprofen 800mg prn Zyrtec PRN Merina IUD Natal Vitamin OTC QD Vitamin D supplement QD
|
1 |
High-Quality Scleroderma PBMC for Research
Scleroderma Human PBMC products are sourced from donors clinically diagnosed with scleroderma (systemic sclerosis) and processed under stringent conditions to support research. These cryopreserved peripheral blood mononuclear cells (PBMCs) enable studies on pathways related to fibrosis, vasculopathy, and immune dysregulation.
Product Features
- Research Use Only (RUO), cryopreserved PBMCs
- Clinically confirmed scleroderma donors
- Available in cell counts ranging from 5 million to 2 billion
- Processed within 24 hours of collection
- Stored using CryoStor® CS10 freezing media
- IRB-approved protocols and electronic informed consent
- Screen LeukoLot™ available prior to bulk orders
De-identified Donor Data
- Verified Scleroderma diagnosis
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Self-reported allergies and infectious disease history
- Additional Scleroderma-specific data available upon request
Applications
- Biomarker discovery and validation
- Drug screening and therapeutic development
- Immune pathway analysis in scleroderma pathophysiology
- Transcriptomic and proteomic profiling
Quality and Compliance
- IRB-approved collections and protocols
- 21 CFR Part 11 – compliant e-consent system
- HIPAA-compliant donor data protection
Ordering & Shipping
Scleroderma PBMC samples are shipped on dry ice and available in custom aliquots. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com to confirm documentation and compliance needs.
Protocols & Documentation
-
Download
PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
-
Download
Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
-
Download
Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
-
Download
Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
-
Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
1 Answer
YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
1 Answer
YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
1 Answer
Our complete catalog can be found here: https://sanguinebio.com/products/
1 Answer
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
1 Answer
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
1 Answer
Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
1 Answer
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
1 Answer
YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
1 Answer
Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
1 Answer
YES – Unique donors can be specified and guaranteed based on your requirements.
1 Answer
For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
1 Answer
YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.