Scleroderma CD4+ T Cells
About:Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with scleroderma. Suitable for research examining immune dysregulation, fibrosis-associated inflammation, and autoimmune connective tissue disease mechanisms.
About Scleroderma CD4+ T Cells
Scleroderma CD4+ T Cells
CD4+ T Cells for Fibrosis and Autoimmune Connective Tissue Research
Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with scleroderma. These helper T lymphocytes contribute to immune dysregulation and fibrosis-associated inflammation characteristic of systemic connective tissue disease. Scleroderma CD4+ T cells are suitable for studies examining immune signaling pathways, cytokine production, and therapeutic strategies targeting autoimmune-driven fibrosis.
Product Features
- Research Use Only (RUO), CD4 positive T cells
- Isolated from clinically confirmed scleroderma donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Treatment background when available
Applications
- Immune dysregulation studies
- Fibrosis-associated inflammation research
- Cytokine signaling analysis
- Autoimmune therapeutic development
- Functional and transcriptomic assays
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Applications
- Immunology and translational research
- Biomarker discovery and validation
- Drug screening and assay development
- Vaccine and infectious disease research
Product Features
- Research Use Only (RUO), CD4+ T Cells
- Sourced from screened, consented donors
- Processed under validated SOPs
- QC tested for purity, viability, and sterility
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Need a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.