Sjogren’s Syndrome CD4+ T Cells
Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Sjögren’s syndrome. Suitable for research on autoimmune inflammation, lymphocyte activation, and immune mechanisms affecting exocrine gland dysfunction.
Sjögren’s Syndrome CD4+ T Cells
CD4+ T Cells for Autoimmune Exocrine Gland Research
Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Sjögren’s syndrome. These helper T cells contribute to chronic autoimmune inflammation targeting salivary and lacrimal glands. Sjögren’s CD4+ T cells are suitable for studies of lymphocytic infiltration, cytokine dysregulation, and immune-mediated glandular dysfunction. Cryopreserved cells support reproducible in vitro assays and immune profiling applications.
Product Features
- Research Use Only (RUO), CD4 positive T cells
- Isolated from clinically confirmed Sjögren’s syndrome donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune activation studies
- Cytokine signaling analysis
- Immune-mediated tissue damage modeling
- Biomarker discovery
- Transcriptomic and functional immune assays
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.