Sjogren’s Syndrome CD8+ T Cells
About: Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Sjögren’s syndrome. Ideal for studies of autoimmune inflammation and immune-mediated tissue damage.
Sjögren’s Syndrome CD8+ T Cells
CD8+ T Cells for Autoimmune Exocrine Gland Research
Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Sjögren’s syndrome. CD8+ cytotoxic lymphocytes contribute to immune-mediated epithelial damage and chronic inflammatory signaling affecting salivary and lacrimal glands. These cells are suitable for studies examining immune dysregulation, cytotoxic activation, and therapeutic modulation of autoimmune responses.
Product Features
- Research Use Only (RUO), CD8 positive T cells
- Isolated from clinically confirmed Sjögren’s syndrome donors
- High purity and viability (≥90% CD8+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune tissue damage modeling
- Cytokine signaling analysis
- Immune activation studies
- Therapeutic response evaluation
- Functional immune assays
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD8+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.