Sjogren’s Syndrome CD56+ NK Cells
Sjogren’s Syndrome CD56 NK Cells are isolated from donors with clinically confirmed Sjogren’s. Ideal for studying NK cell infiltration in exocrine glands and their role in epithelial damage and autoimmunity.
Sjogren’s Syndrome CD56 NK Cells for Autoimmune and Immunopathology Research
Sjogren’s Syndrome CD56 NK Cells are cryopreserved from peripheral blood of IRB-consented adult donors diagnosed with Sjogren’s Syndrome. These CD56+ CD3− natural killer (NK) cells reflect disease-associated immune alterations and offer a critical resource for studying immune surveillance, inflammation, and cytotoxicity in the context of Sjogren’s Syndrome.
Product Features
- Research Use Only (RUO), CD56+ enriched NK cells
- Isolated from clinically diagnosed Sjogren’s Syndrome donors
- High viability and enrichment
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- Ethically sourced with IRB approval and HIPAA compliance
De-identified Donor Data
- Confirmed diagnosis of Sjogren’s Syndrome
- Demographics: age, sex assigned at birth, race/ethnicity
- Self-reported clinical history and medication use
Applications
- Investigation of NK cell phenotypes and function in Sjogren’s Syndrome
- Cytotoxicity, immune exhaustion, and single-cell analysis
- Disease mechanism studies and biomarker identification
- Preclinical immunotherapy development
Compliance and Quality Assurance
- IRB-approved collection and 21 CFR Part 11–compliant e-consent
- Standardized processing and quality protocols
- HIPAA-compliant data handling
Ordering & Customization
Sjogren’s Syndrome CD56 NK Cells are offered in standard or custom aliquot sizes. For regulatory documentation or international support, contact learnmore@sanguinebio.com.
Protocols & Documentation
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Download
Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD56+ NK Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.