Human Immunodeficiency Virus HIV CD4+ T Cells
About: Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors living with human immunodeficiency virus (HIV). Ideal for studies of viral-host interactions, immune activation, T cell depletion, and antiviral therapeutic development.
Human Immunodeficiency Virus (HIV) CD4+ T Cells
Disease-State CD4+ T Cells for Viral Immunology Research
Human CD4+ T Cells are purified from peripheral blood of IRB-consented donors living with human immunodeficiency virus (HIV). As primary targets of HIV infection, CD4+ T cells are essential for studying viral-host interactions, immune activation, latency mechanisms, and therapeutic intervention strategies.
These cells support investigations into viral reservoir dynamics, immune exhaustion, and antiviral drug development. Cryopreserved cells maintain high viability and consistent performance for downstream assays.
Product Features
- Research Use Only (RUO), CD4 positive T cells
- Isolated from clinically confirmed HIV-positive donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and health history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Treatment status when available
Applications
- HIV infection and latency modeling
- Immune activation and exhaustion studies
- Antiviral therapeutic development
- Viral reservoir research
- Molecular and transcriptomic profiling
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.