Human Immunodeficiency Virus HIV CD8+ T Cells
About: Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors living with human immunodeficiency virus (HIV). Suitable for viral immunology studies, immune exhaustion research, and antiviral response characterization.
Human Immunodeficiency Virus (HIV) CD8+ T Cells
Disease-State CD8+ T Cells for Viral Immunology Research
Human CD8+ T Cells are purified from peripheral blood of IRB-consented donors living with human immunodeficiency virus (HIV). CD8+ cytotoxic T lymphocytes are central to antiviral immune responses and play a significant role in viral control and immune exhaustion dynamics. These cells support investigations into viral-host interactions, immune activation pathways, therapeutic interventions, and immune modulation strategies. Cryopreserved cells maintain high viability and reproducible performance for downstream functional assays.
Product Features
- Research Use Only (RUO), CD8 positive T cells
- Isolated from clinically confirmed HIV-positive donors
- High purity and viability (≥90% CD8+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and health history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Treatment status when available
Applications
- Antiviral cytotoxic response studies
- Immune exhaustion research
- Viral reservoir modeling
- Therapeutic development and evaluation
- Molecular and transcriptomic profiling
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD8+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.