Type 1 Diabetes CD4+ T Cells
About:Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Type 1 diabetes. Appropriate for investigations of autoimmune beta-cell destruction, antigen-specific immune responses, and T cell–mediated metabolic disease mechanisms.
About Type 1 Diabetes CD4+ T Cells
Type 1 Diabetes CD4+ T Cells
Disease-State CD4+ T Cells for Autoimmune and Metabolic Research
Human CD4+ T Cells are purified from peripheral blood of IRB-consented donors clinically diagnosed with Type 1 diabetes (T1D). These helper T lymphocytes are central to autoimmune-mediated pancreatic beta-cell destruction and antigen-specific immune activation. T1D CD4+ T cells support investigations into immune tolerance mechanisms, autoreactive T cell responses, cytokine signaling pathways, and therapeutic strategies aimed at modulating autoimmune diabetes. Cryopreserved cells provide high viability and consistent functional performance for in vitro immune assays and molecular profiling.
Product Features
- Research Use Only (RUO), CD4 positive T cells
- Isolated from clinically confirmed Type 1 diabetes donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and health history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune antigen response studies
- Immune tolerance research
- Beta-cell immune interaction modeling
- Immunotherapy development
- Single-cell and transcriptomic analysis
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Applications
- Immunology and translational research
- Biomarker discovery and validation
- Drug screening and assay development
- Vaccine and infectious disease research
Product Features
- Research Use Only (RUO), CD4+ T Cells
- Sourced from screened, consented donors
- Processed under validated SOPs
- QC tested for purity, viability, and sterility
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Need a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.