Healthy CD4+ T Cells

Healthy CD4+ T Cells

Disease-State Human CD4+ T Cells for Autoimmune Immunology Research

Human CD4+ T Cells are purified from peripheral blood of IRB-consented donors clinically diagnosed with systemic lupus erythematosus (SLE). These helper T lymphocytes play a central role in autoimmune pathogenesis through abnormal activation, cytokine dysregulation, and loss of immune tolerance. SLE CD4+ T cells support investigations of autoreactive immune responses, immune signaling pathways, and therapeutic modulation of systemic autoimmunity. Cryopreserved cells provide high viability and reproducible performance for downstream functional and molecular assays.

Product Features

  • Research Use Only (RUO), CD4 positive T cells
  • Isolated from clinically confirmed SLE donors
  • High purity and viability (≥90% CD4+ cells)
  • Cryopreserved in CryoStor® CS10 media
  • Processed within 24 hours of collection
  • IRB-approved protocols with electronic informed consent

Donor Metadata

  • Verified clinical diagnosis and health status
  • Demographic data: age, sex assigned at birth, race/ethnicity
  • Self-reported medication and treatment history when available

Applications

  • Autoimmune T cell activation studies
  • Cytokine signaling analysis
  • B–T cell interaction research
  • Biomarker discovery and therapeutic development
  • Single-cell and transcriptomic analysis

Compliance and Quality Assurance

  • IRB-approved collections and standardized procedures
  • 21 CFR Part 11–compliant e-consent system
  • HIPAA-compliant data management

Ordering & Customization

Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.

Healthy Publications

Frequently Asked Questions

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Do samples come with donor screening reports?

1 Answer

All our samples have self-reported infectious disease testing and verified clinical diagnosis. Many of our samples have the option of electronic medical records provided and our prospective collection offers the opportunity for patient reported outcomes and surveys. Learn more here. https://sanguinebio.com/patient-reported-outcomes-pro-surveys-questionnaires/

YES – Certificate of analysis is available upon request.

Lead times vary from ready to ship inventory to prospective studies.

International shipping is available. We also work with a number of distributors. Contact us to discuss options at learnmore@sanguinebio.com.

We have several ordering methods. You can order directly online with a PO or credit card or contact us to have a sales specialist help with your order. https://sanguinebio.com/request-quote/

You can request a quote on this page or contact us at learnmore@sanguinebio.com. https://sanguinebio.com/request-quote/

NO – no minimum order requirements.

For bulk pricing inquiries, please contact: LearnMore@sanguinebio.com

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Need a custom CD4+ T Cells cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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