PBMC

PBMC

In Stock · 500

About: Human PBMCs for Research Human PBMC samples are collected from healthy and clinically confirmed disease-state donors, then cryopreserved to preserve viability and function. Sanguine’s PBMCs are designed to support a wide range of research applications, from immune profiling and cytokine analysis to cell-based assays and therapeutic development.

IRB-approved Worldwide shipping Full donor metadata

In Stock Samples

Lot Number Condition Cell Count (M) Race/Ethnicity Age Gender Country of Collection Medications Vials Price Action
77120 Sjogren's Syndrome 10M Caucasian 54 Female
Omeprazole 20mg QD Bupropion XL 300mg QD Repatha 140mg Q2W Armour thyroid 60mg QD Hydroxychloroquine 200mg QD Azothioprene 50mg TID Bictoza 18mg QD Rizotriptan PRN Buprion 15mg QD Vraylar 300mg QD Methylphenidate 20mg QD Zoloft ? QD
 80 $530.00
74269 Sjogren's Syndrome 10M Hispanic/Latino 52 Female
Dexilant 30 mg QD Reglan 10mg BID Famotidine 40 mg QD Progesterone 200 mg QD
 2 $530.00
60197 Systemic Lupus Erythematosus (SLE) 25M Caucasian 51 Female
Plaquenil 300mg qd Imuran 100mg qd Trazodone 50mg Omeprazole 20mg qd
 17
74427 Sjogren's Syndrome 10M Caucasian 63 Female
Atorvastatin 20 mg Omeprazole 40 mg Levothyroxine 88 mcg Trazadone 50 mg Nortriptyline 10 mg Singulair 10 mg Cymbalta 50 mg Vitamin C Methotrexate 2.5 mg Adderall XR 30 mg BID Vivitrol QM-Has not taken since November Collagen Keratin Multivitamin (Cerefolin - Brain Food) Prazosin 1mg QD
 12 $530.00
60686 Systemic Lupus Erythematosus (SLE) 10M Caucasian 52 Female
Fluoxetine 20 mg BID Lisinopril 20 mg BID Leflunomide 20 mg QD Plaquenil 200 mg QOD Amovig 120 mg QM Bentyl PRN Ibuprofen PRN Saphnelo Amlodipine 2.5 mg BID Multivitamin CoQ10 Fish oil
 4 $530.00
57431 Multiple Sclerosis 5M Caucasian 69 Female
Copaxone shots 40 mg TIW Cymbalta 60mg QD Lorazapam 0.5mg PRN Fioricet 300 mg PRN Melatonin 10 ml QD Myrbetriq 25mg QD LDN 3 mg QD Ocuvite QD Pilocarpine 5mg QD Mounjaro 2.5mg QW Simvastatin (Zocor) 10mg QD Cranberry 450mg QD - preventative for UTI Omega 3 QD Thiamin HCl QD Vitamin D2 QD Miralax PRN Meloxicam/QD COVID 19 vaccine Moderna 2022
 25
73833 Systemic Lupus Erythematosus (SLE) 10M Hispanic/Latino 40 Female
Plaquenil Wellbutrin Cymbalta Xyzal
 66 $530.00
70009 Myositis 10M Caucasian 64 Female
Azathioprine Venlafaxine Rosuvastatin Sumatryptin PRN Vitamin D3 Folic Acid Biotin Probiotic
 60 $765.00
55550 Atopic Dermatitis (Eczema) 50M Hispanic/Latino 44 Male 35 $1,109.00
75950 Multiple Myeloma 10M Hispanic/Latino 56 Female 14
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High-Quality PBMCs for Research

Human PBMCs are sourced from healthy and disease-state donors and processed under controlled conditions to support high-quality research. These cryopreserved peripheral blood mononuclear cells enable studies in immune function, cytokine response, biomarker discovery, cell therapy research, and therapeutic screening.

Whether you need PBMCs as matched controls, disease-state comparators, or custom donor-defined samples, Sanguine helps research teams source PBMCs aligned to protocol requirements and downstream assay needs.

What Is a PBMC?

A peripheral blood mononuclear cell (PBMC) is any blood cell with a round nucleus — including lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells. PBMCs are isolated from whole blood or a leukopak by density-gradient separation, which removes red blood cells and granulocytes. Because they contain the key effector cells of the immune system, human PBMCs are one of the most widely used starting materials in immunology, immuno-oncology, and cell and gene therapy research.

Product Features

  • Research use only cryopreserved human PBMCs
  • Sourced from healthy and disease-state donors
  • Available in cell counts ranging from 5 million to 2 billion
  • Processed within 24 hours of collection
  • Preserved using CryoStor CS10 freezing media
  • Designed to support cell viability and functional assays
  • IRB-approved protocols and electronic informed consent
  • Screening and bulk-order support available for larger PBMC programs

De-identified Donor Data

Available donor-level information helps researchers select PBMC samples that align to study design and population requirements.

  • Donor demographics including age, sex assigned at birth, and race/ethnicity
  • Self-reported allergies and infectious disease history
  • Healthy donor and disease-state context where applicable
  • Additional donor-specific data available upon request
  • Study-specific donor requirements may be supported for custom programs

Applications

Human PBMCs support a broad range of immunology and translational research workflows.

  • Biomarker discovery and validation
  • Drug screening and therapeutic development
  • Immune pathway analysis
  • Cytokine and functional immune assays
  • Transcriptomic and proteomic profiling
  • Cell-based assay development
  • Matched control and disease-state comparison studies

Disease-State PBMC Samples

Sanguine offers PBMCs from donors with confirmed diagnoses across a range of conditions, including:

For related products, see our human leukopak and human whole blood.

Quality and Compliance

  • IRB-approved collections and protocols
  • 21 CFR Part 11-compliant electronic informed consent
  • HIPAA-compliant donor data protection
  • Controlled processing workflows designed to support PBMC quality
  • Documentation available for qualified research programs

Ordering & Shipping

Human PBMC samples are shipped on dry ice and are available in multiple cryopreserved configurations to support a range of research needs. If your project requires custom aliquots, larger bulk orders, or international documentation, our team can help identify the right fulfillment path. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com.

Buy Human PBMCs for Research

Sanguine is a trusted supplier of human PBMCs for research, offering healthy and disease-state PBMC samples from a community of 70,000+ donors. Purchase fresh or cryopreserved patient PBMCs with full donor data, or commission a custom PBMC collection built to your inclusion/exclusion criteria. Browse in-stock PBMC samples above or request a quote to buy PBMCs for your study.

Frequently Asked Questions About Buying PBMCs

How do I buy PBMCs for research?

Browse the in-stock human PBMC samples above or request a quote. Sanguine supplies fresh and cryopreserved PBMCs from healthy and disease-state donors, with custom collections available to your study criteria.

Do you offer disease-state and patient PBMCs?

Yes. We provide disease-state and patient PBMC samples across 100+ confirmed conditions, plus healthy controls — see the disease-state PBMC list above or request a custom cohort.

Are PBMC samples available for sale fresh and cryopreserved?

Yes. Human PBMC samples are available for purchase in both fresh and cryopreserved formats, in cell counts ranging from 5 million to 2 billion per vial.

Protocols & Documentation

  • PBMC Isolation from Whole Blood

    Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.

    Download

  • Immune Cell Isolation

    Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.

    Download

  • Choosing the Right PBMC Configuration

    Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.

    Download

  • Thawing Cryopreserved PBMC

    Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.

    Download

  • Informed Consent Form (ICF)

    Available upon request — confirms donor consent for research use and downstream commercialization.

PBMC

Frequently Asked Questions

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Do PBMCs come with flow cytometry data, clinical patient information, or treatment status details?

1 Answer

Electronic medical records are an option to be included with the PBMC sample, as well as, flow cytometry and other phenotypic testing.

YES – we can often accommodate treatment-naive samples including various cancers, and you can specify immunosupression status or other requirements in the I/E criteria.

Self-reported infectious disease testing is always available and some of our products have additional testing.

HLA-typing is available for some of our PBMC products.

YES to both – Unique donors can be specified, and multiple vials from the same donor can be arranged. You can specify these requirements when ordering.

Healthy PBMCs achieve over 90% vialbity post-thaw. Although our disease-state PBMCs are processed with same stringent SOP, there is more variability depending upon disease. Learn more about our post thaw viability here. https://sanguinebio.com/pbmc-viability-quality-assurance/

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Need a custom PBMC cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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