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Whole Blood Phospho-flow: Direct Ex Vivo Measurement of Signaling in PBMC
I previously discussed phospho-flow cytometry, a method to study intracellular…
GEM T cells: A newly identified class of restricted α-chain TCRα/β T cells
The diversity of the T cell repertoire allows for recognition…
Highlight: Is too much salt bad for your guts?
Whether eating too much table salt in our diet is…
Tumor Immunotherapies Combine Big for Synergy in Phase I Trials
There are currently two immune cell targeting immunotherapeutic agents that…
A unique set of cell surface markers for induced T regulatory cells
Transplantation of antigen-specific T cells during cancer immunotherapy has generated…
Identification of New Potential Drug Targets for Treatment of Lupus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that afflicts…
Computers meet T cells: in silico identification of mutated tumor antigens targeted by T cells
It is well accepted that T cells can recognize and…
A bifunctional FoxP3+ regulatory T cell subset converts to pro-inflammatory helper T cells
Recently a number of studies have arisen characterizing various functional…
A theory of everything: commensal gut bacteria link environmental exposures to sex hormones in modulating autoimmunity
Whether an individual develops autoimmunity depends on how environmental and…