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Induction of Tumor cell senescence by TH1 cytokines IFN-g and TNF
Interferons, including type I (IFNα/β) and type II (IFNγ) are…
Development of Anti-viral CD4+ T cells in unexposed individuals
In a study published in the February 2013 issue of…
The Shock of Sepsis: The Struggle to Treat SIRS
Since the mid-1880’s, scientists and clinicians have studied the concept…
Unique anti-tumor functions of IFNg vs. IL-17 producing CD8 cells
The anti-tumor effectiveness of IFNγ-producing CD4+ TH1 cells and CD8+…
T cell dysfunction in cancer: Anergy, Exhaustion, or Senescence?
Immune responses against cancer have been shown to be effective…
Upcoming Immunology Conferences: March – June, 2013
I previously posted about 2013 Conferences in Tumor Immunology and…
New role for p53 in regulating the inflammatory tumor microenvironment
p53 (TP53), a transcription factor activated by various types of…
Signal amplification loops in chronic inflammation and Colon Cancer
The inflammatory gastrointestinal diseases Crohn’s disease, inflammatory bowel diseases (IBD),…
Antagonism of Tumor-Immunity by Chemotherapeutics
Significant steps forward are being made in immunotherapeutic approaches for…