Celiac Disease CD8+ T Cells

Celiac Disease CD8+ T Cells

CD8+ T Cells for Autoimmune Gastrointestinal Research

Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with celiac disease. CD8+ cytotoxic lymphocytes contribute to antigen-driven immune activation and intestinal epithelial damage associated with gluten sensitivity. These cells are valuable for investigating inflammatory signaling pathways, antigen-specific responses, and immune-mediated gastrointestinal pathology.

Product Features

  • Research Use Only (RUO), CD8 positive T cells
  • Isolated from clinically confirmed celiac disease donors
  • High purity and viability (≥90% CD8+ cells)
  • Cryopreserved in CryoStor® CS10 media
  • Processed within 24 hours of collection
  • IRB-approved protocols with electronic informed consent

Donor Metadata

  • Verified diagnosis and clinical history
  • Demographic data: age, sex assigned at birth, race/ethnicity
  • Medication and dietary background when available

Applications

  • Antigen-specific immune response studies
  • Intestinal inflammation modeling
  • Cytotoxic pathway analysis
  • Autoimmune mechanism research
  • Single-cell immune profiling

Compliance and Quality Assurance

  • IRB-approved collections and standardized procedures
  • 21 CFR Part 11–compliant e-consent system
  • HIPAA-compliant data management

Ordering & Customization

Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.

Frequently Asked Questions

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Do samples come with donor screening reports?

1 Answer

All our samples have self-reported infectious disease testing and verified clinical diagnosis. Many of our samples have the option of electronic medical records provided and our prospective collection offers the opportunity for patient reported outcomes and surveys. Learn more here. https://sanguinebio.com/patient-reported-outcomes-pro-surveys-questionnaires/

YES – Certificate of analysis is available upon request.

Lead times vary from ready to ship inventory to prospective studies.

International shipping is available. We also work with a number of distributors. Contact us to discuss options at learnmore@sanguinebio.com.

We have several ordering methods. You can order directly online with a PO or credit card or contact us to have a sales specialist help with your order. https://sanguinebio.com/request-quote/

You can request a quote on this page or contact us at learnmore@sanguinebio.com. https://sanguinebio.com/request-quote/

NO – no minimum order requirements.

For bulk pricing inquiries, please contact: LearnMore@sanguinebio.com

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Need a custom CD8+ T Cells cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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