Apheresis Collection: Healthy and Disease-State

High quality, RUO and GMP leukopaks from our diverse network of donors

Process Development
Process Development
Cell & Gene Therapy
Cell & Gene Therapy
Assay Validation
Assay Validation
Rare Cell Isolation
Rare Cell Isolation

Leukopaks: One Donor, Billions of White Blood Cells

Large volumes of white blood cells can be separated by apheresis (leukapheresis) while plasma and red blood cells are returned to the donor. Leukapheresis products collected from the same donor provide a reliable and consistent source of up to 10 billion immune cells, including peripheral blood mononuclear cells (PBMCs), and rare cells, as well as for biomarker discovery, immunology, autologous, and allogeneic cell therapy research, product development, and manufacturing.

GMP leukopaks has launched.LeukoCore, LeukoCert and LeukoLot

Leukopaks from our network of 70,000+ donors

Diverse Donor Network
Diverse Donor Network
  • 70,000 patient and healthy donors nationwide
  • Confirmed disease diagnosis via medical record
  • Medical histories
  • Inclusion/Exclusion criteria
  • Mechanisms to screen donors for distinct biomarker signatures
Comprehensive Donor Data
Comprehensive Donor Data
  • Annotated medical records
  • Study-specific questionnaires
  • Infectious disease status
  • HLA typing class 1 & 2
  • Complete blood count (CBC)
  • Total Nucleated Cell Count (TNC)
  • Demographics
Quality
Quality
  • Adherence to standards and protocols ensures high cell viability & recovery
  • Certificate of Analysis
  • Same-day or next-day shipment
  • Up to 10 billion (full) or 5 billion (half) total nucleated cells per leukopak
Recallable Donors
Recallable Donors
  • Longitudinal studies with multiple time points
  • Concurrent collection of additional sample types (e.g., urine, stool, skin tapes)
  • Nationwide network of qualified apheresis clinics

Additional characterization & isolation capabilities, including:

rarity of the condition
Mononuclear cell isolation (PBMCs, T, B, and/or NK cells)
Diverse menu of CLIA-certified diagnostic tests
100+ additional CLIA-certified diagnostic tests
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Percent abundance characterization of immune cell subtypes

Diagnosed Conditions for Apheresis

  • Age-related Macular Degeneration (AMD)
  • Allergies
  • Arthritis
  • Asthma
  • Atopic Dermatitis (Eczema)
  • Celiac Disease
  • CIDP (Chronic inflammatory demyelinating polyneuropathy)
  • Chronic Kidney Disease
  • COPD (Chronic obstructive pulmonary disease)
  • Crohn's Disease
  • Cystic Fibrosis
  • Diabetes Type 1
  • Diabetes Type 2
  • Fibromyalgia
  • Gout
  • Hashimoto's Disease
  • Healthy Control
  • Hepatitis B
  • Hepatitis C
  • Hidradenitis Suppurativa
  • HIV
  • Hypercholesterolemia (High Cholesterol)
  • Hypertension (High Blood Pressure/HBP)
  • Hypothyroidism
  • Lupus (SLE)
  • Lupus Nephritis
  • Multiple Sclerosis
  • Osteoarthritis
  • Psoriasis
  • Psoriatic Arthritis
  • Pulmonary Hypertension
  • Rheumatoid Arthritis
  • Scleroderma
  • Sjogren's Syndrome
  • Ulcerative Colitis
  • Vitiligo

Compliance & Quality Assured

For quality and compliance related information, please visit Sanguine quality and compliance page.

For privacy related information, please visit Sanguine privacy policy page.

Publications using Sanguine PBMCs:

Cell

Profiling SARS-CoV-2
HLA-I peptidome
reveals T cell epitopes
from out-of-frame
ORFs

>

Nature Communications

A novel PD-L1 inhibitor stimulated immune cell responses in donor PBMCs from HBV-positive (T cells) and HBV-vaccinated (B cells) patients

>

Lupus Patient Advocacy

Request A Quote for Sanguine Leukopaks

To provide you with an accurate quote, please complete the short form.

Alternatively, to speak with someone directly, please contact:

Phone: 818-462-8290

Email: LearnMore@sanguinebio.com

Other Services

Human PBMCs
Human Serum and Plasma
Employer Onsite Collection Programs
Longitudinal Sampling & Event-Based Collection
Lymphocyte Isolation
Noninvasive Skin Tapes
Mobile Biospecimen Collection
PBMCs Isolation Services for Clinical Trials