Graves’ Disease PBMC
Powered by BiozAbout:Graves' Disease PBMC are sourced from consented donors with documented Graves' disease. These samples support immune-cell research, with donor information on condition, demographics, medications and comorbidities.
About Graves’ Disease PBMC
Graves’ Disease PBMC are sourced from consented donors with documented Graves’ disease. These samples support immune-cell research, with donor information on condition, demographics, medications and comorbidities.
Applications
- Graves’ Disease research
- Immune-cell phenotyping
- Cellular functional assays
- Single-cell and bulk transcriptomics
- Drug-response research
Product Features
- Peripheral blood mononuclear cells
- Donor condition: Graves’ Disease
- Consented donor collection
- Research Use Only (RUO)
De-identified Donor Data
- Donor condition/diagnosis and documented clinical phenotype
- Age, gender and race/ethnicity
- Medications and comorbidities
- HLA typing and CMV status
- HIV, HBV, HCV and syphilis testing
- ABO/Rh blood type and country of collection
- Tobacco, alcohol, caffeine and recreational drug use
Donor Stratification
Cohort characteristics include diagnosis and documented clinical phenotype, medication history, comorbidities and demographics.
Processing specifications
- Anticoagulant
- Confirmed per lot on request
- Isolation
- Density-gradient centrifugation (SepMate™); optional RBC lysis
- Processing window
- Processed within ~24 hours of collection unless otherwise stated
- Cryopreservation
- Cryopreservation medium with 10% DMSO; controlled-rate freezing (−1 °C/min)
- Storage
- Vapor-phase liquid nitrogen
- Count and viability
- Automated dual-fluorescence cell counter; cells per vial listed per lot
- Aliquot sizes
- 5 × 10⁶ cells (vial)1 × 10⁷ cells (vial)5 × 10⁷ cells (vial)2 × 10⁹ cells (bulk vials)
From Sanguine's processing protocols. View protocols
Donor and clinical data in these lots
Fields recorded on the 7 in-stock lots for this product. Coverage varies by donor; blank fields are not available for that lot.
Donor
- Sex
- 7 of 7 lots
- Age
- 7 of 7 lots
- Race
- 7 of 7 lots
- BMI
- 7 of 7 lots
Clinical history
- Primary diagnosis
- 7 of 7 lots
- Current medications
- 6 of 7 lots
- Comorbidities
- 1 of 7 lots
- Allergies
- 7 of 7 lots
- Infectious disease history
- 7 of 7 lots
Lab results & genotype
- CMV serostatus
- 5 of 7 lots
- ABO / Rh blood type
- 5 of 7 lots
- HLA class I typing
- 5 of 7 lots
- HLA class II typing
- 3 of 7 lots
- Flow cytometry immunophenotype
- 2 of 7 lots
Lifestyle
- Tobacco use
- 7 of 7 lots
- Alcohol use
- 7 of 7 lots
- Recreational drug use
- 7 of 7 lots
- Caffeine use
- 7 of 7 lots
Collection
- Collection date
- 7 of 7 lots
- Country of collection
- 7 of 7 lots
Need a field that isn't listed, such as disease stage or time since diagnosis?
Protocols & Documentation
-
Download
PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
-
Download
Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
-
Download
Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
-
Download
Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
-
Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
Ask a Question
Pair with a Healthy Control
Match your Graves' Disease PBMC with normal donor samples for comparison
Healthy Donor PBMCs
733 In Stock View InventoryNeed a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.