RESPIRATORY & METABOLIC CONDITIONS BIOSPECIMENS
Respiratory & Metabolic
Conditions Biospecimens
Accelerating research into diabetes, COPD, asthma, chronic kidney
disease, and related metabolic disorders with premium-quality
samples and comprehensive genomic annotation
Access ethically sourced biospecimens from confirmed diagnoses across the
United States. Support your research from study design to receipt of samples with
our comprehensive portfolio of respiratory and metabolic disease specimens.
Access a comprehensive portfolio of respiratory and metabolic disease biospecimens
Our Donor Network across the United States supports research into major respiratory conditions such as COPD and asthma, metabolic disorders including Type 1 and Type 2 diabetes, endocrine conditions like hypothyroidism and hyperthyroidism, cardiovascular metabolic diseases including hypertension and hypercholesterolemia, and renal complications such as chronic kidney disease and diabetic nephropathy. Whether you need cross-sectional or longitudinal collections, matched sample sets, or custom cohorts, we provide the precise specimens and comprehensive genomic annotation required for breakthrough research in respiratory and metabolic medicine.
Why Choose Sanguine for Respiratory & Metabolic Disease Specimen Solutions
Respiratory and metabolic disease research demands high-quality biospecimens, rigorous patient annotation, and compliance with ethical standards.
Direct-to-Patient Model & Engaged Network
Our network across the United States allows access to well-characterized patients with confirmed diagnoses, streamlining procurement from study design to receipt of samples so you can focus on discovery.
Custom collection services
If what you need isn't available in our inventory, we will recruit and collect from a custom cohort tailored to your specific inclusion/exclusion criteria, supporting your research from initial planning through sample delivery.
Access to Hard-to-Find Populations
Confirmed respiratory conditions, early vs. late-stage metabolic disorders, treatment-naïve vs. treated populations, rare endocrine conditions like AIP (Acute Intermittent Porphyria), — we work with you to source the right patients.
Matched Sample Sets
Get multiple sample types from the same patient (e.g., whole blood, plasma, PBMCs, serum) for holistic biomarker analysis and comprehensive metabolic profiling.
Comprehensive Clinical & Molecular Annotation
Receive samples paired with rich patient data — demographics, confirmed disease history, treatment and outcomes, lab values (HbA1c, lipid panels, kidney function), and imaging when available. Our genomic annotation provides the depth needed for precision medicine research.
Ethical Sourcing & Regulatory Compliance
Our processes meet high ethical and data-security standards (ISO 9001, ISO 27001, ISO 27701 certifications, HIPAA compliance) which gives you confidence in your research tools.
Respiratory & Metabolic Disease Specimen Portfolio
Available Specimen Types Include:
Plasma & Serum
Ideal for biomarker discovery, metabolic profiling, hormone analysis, and inflammatory marker studies
Whole Blood & PBMCs
Perfect for genomic studies, immune profiling, gene expression analysis, and cellular research
Additional Specimen Types
Longitudinal (serial) collections to track natural history and response to intervention
Monitor disease progression, treatment response, and metabolic changes over time with matched patient samples collected at multiple timepoints.
Specimen Type Details
Whole Blood
Available in EDTA, heparin,
or custom anticoagulants
Plasma
K2EDTA or sodium
heparin
Serum
SST or plain red
top tubes
PBMCs
Cryopreserved
(5M-50M cells per vial)
All specimens are processed using standardized protocols within optimized timeframes to ensure maximum quality and viability
Rich Clinical and Molecular Annotation
Many of our respiratory and metabolic biospecimens come with detailed patient documentation, enabling them to function as true translational research tools.
Demographics & clinical characteristics
Confirmed diagnosis and stage, age at diagnosis, gender, race/ethnicity, family history, comorbidities, body mass index (BMI), smoking status, lifestyle factors
Treatment history
Medication exposures (e.g., insulin, metformin, bronchodilators, corticosteroids, statins, antihypertensives), device usage (e.g., CPAP, insulin pumps), surgical interventions, therapy changes, adherence data
Laboratory Data & Metabolic Profiling
HbA1c levels, fasting glucose, lipid panels (total cholesterol, LDL, HDL, triglycerides), kidney function markers (eGFR, creatinine, albuminuria), thyroid function tests (TSH, T3, T4), C-peptide, inflammatory markers (CRP, IL-6), pulmonary function tests (FEV1, FVC), blood gas analysis
Molecular profiling
Where available, data may include biomarker levels, genetic or genomic data, gene expression profiles, metabolomics data, proteomic analysis, epigenetic markers
Outcomes data
Natural history tracking, glycemic control trends, pulmonary function decline rates, cardiovascular events, renal function progression, hospitalization records, treatment response metrics, longitudinal follow-up data
Supporting Research Across Major Respiratory & Metabolic Conditions
Diabetes Research (Type 1 & Type 2)
Support research into insulin resistance, beta-cell dysfunction, glycemic control, complications prevention, novel therapeutic development, and precision medicine approaches for diabetes management.
Ethical Sourcing and Regulatory Compliance
Trust and compliance are fundamental to our operations.
Ethical standards:
- Institutional Review Board (IRB)-approved patient consent documentation
- Patients engaged through transparent, compliant recruitment and consent processes
- All samples from confirmed diagnoses, never suspected conditions
- Rigorous quality control throughout the collection and processing workflow
Regulatory & Data Security
- De-identified patient data in HIPAA-compliant format
- Certified quality management systems including ISO 9001, ISO 27001, ISO 27701 for information security and privacy
- Full chain of custody documentation
- Compliance with all applicable federal and state regulations
Reference:
Sanguine Biosciences' commitment to quality and compliance is demonstrated through our ISO certifications for quality management, information security, and privacy protection.
From Discovery to Therapy — Powering Every Step of Respiratory & Metabolic Research
Whether you're exploring disease mechanisms, developing diagnostics, or validating therapeutic strategies, our biospecimens support research across the respiratory and metabolic disease continuum:
Basic research
Investigate mechanisms of metabolic dysfunction, insulin signaling pathways, inflammatory responses in respiratory disease, hormone regulation, lipid metabolism, renal pathophysiology
Biomarker discovery & validation
Use longitudinal sets and matched controls to identify prognostic or predictive markers for disease onset, progression, and treatment response (e.g., HbA1c, inflammatory cytokines, renal injury markers, lipid biomarkers)
Therapeutic development
Support drug discovery and clinical validation with well-characterized patient samples, treatment-naïve and treated cohorts, matched pre- and post-treatment samples
Precision Medicine
Leverage genomic profiling in samples linked to phenotypic and outcomes data to enable precision medicine approaches for personalized treatment strategies
Diagnostics development
Develop and validate assays for early detection, risk stratification, disease monitoring, and treatment response assessment across respiratory and metabolic conditions
Ready to Advance Your Respiratory & Metabolic Disease Research?
Our patient network across the United States supports comprehensive research into respiratory and metabolic conditions. Whether you need cross-sectional or longitudinal collections, matched sample sets, or custom cohorts, we provide the precise specimens and comprehensive genomic annotation required for breakthrough research.