Sanguine Disease State Leukopaks

High-quality, high-volume, patient-centric, RUO leukapheresis products
from our diverse network of research-ready study participants


Disease State Leukopaks

Research Use Only (RUO) leukapheresis products collected from the same donor provide a reliable and consistent source of up to 10 billion peripheral blood mononuclear cells (PBMCs), including rare CD34+ cells, for biomarker, immunology, autologous, and allogeneic cell therapy research and product development.

Assay Validation
Assay Validation
Process Development
Process Development
Rare Cell Isolation
Rare Cell Isolation
Cell & Gene Therapy
Cell & Gene Therapy

Leukopaks from our network of 60,000+ donors

Diverse Donor Network
Diverse Donor Network
  • 60,000+ donors nationwide
  • Confirmed disease diagnosis via medical record
  • Medical histories
  • Inclusion/Exclusion criteria
Comprehensive Donor Data
Comprehensive Donor Data
  • Medical records
  • Demographics
  • Patient reported outcomes
  • Surveys & questionnaires
  • Viral tested donors (HIV, HBV, HCV)
  • Certificate of analysis reports on cell viability & recovery
  • Cryopreserved or fresh
  • Same-day or next-day shipment
  • Up to 10 billion PBMCs per pack
Recallable Donors
Recallable Donors
  • Longitudinal studies with multiple time points
  • Concurrent collection of additional sample types (e.g., urine, stool, skin tapes)
  • Nationwide network of qualified apheresis clinics

Confirmed Disease State Leukopaks Collected Under IRB Protocols

  • Systemic Lupus Erythematosus (SLE) Leukopaks
  • Rheumatoid Arthritis (RA) Leukopaks
  • Ulcerative Colitis (UC) Leukopaks
  • Crohn’s Disease (CD) Leukopaks
  • Atopic Dermatitis (AD) Leukopaks
  • Asthma Leukopaks
  • Celiac Disease Leukopaks
  • Multiple Sclerosis (MS) Leukopaks
  • Psoriasis Leukopaks
  • Diabetes Mellitus (DM) Type 1 and Type 2 Leukopaks
  • Human Immunodeficiency Virus (HIV) Leukopaks
  • Hepatitis B Virus (HBV) Leukopaks

Additional characterization & isolation capabilities, including:

Human Leukocyte Antigen (HLA) typing
Human Leukocyte Antigen (HLA) typing
Diverse menu of CLIA-certified diagnostic tests
Diverse menu of CLIA-certified diagnostic tests
Percent abundance characterization of immune cell subtypes

Trust Sanguine for Your Human Sample Research Needs:

Compliance & Quality Assured

Our informed consent protocol is 21 CFR 11-compliant, and our organization maintains the gold standard AAHRPP accreditation for protecting research participants. All Sanguine practices are HIPAA-compliant. Leukapheresis is conducted under an IRB-approved protocol at Sanguine-partnered, FDA-qualified blood clinic sites.

FDA logo
HIPAA logo

More than Biospecimen Procurement

Take advantage of our experienced and dedicated sample collection, logistics, processing, characterization, and storage capabilities to optimize and streamline your study design and mitigate unnecessary variability.

Publications using Sanguine PBMCs:


Profiling SARS-CoV-2
HLA-I peptidome
reveals T cell epitopes
from out-of-frame


Nature Communications

A novel PD-L1 inhibitor stimulated immune cell responses in donor PBMCs from HBV-positive (T cells) and HBV-vaccinated (B cells) patients


Hear from our Community:

Learn More about Sanguine Leukopaks

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Alternatively, to speak with someone directly, please contact:

Phone: 818-462-8290


Other Services

Human PBMCs
Human Serum and Plasma
Lab Capabilities
Longitudinal Sampling & Event-Based Collection
Lymphocyte Isolation
Noninvasive Skin Tapes
Patient-Powered Biospecimens and Data
PBMCs Isolation Services for Clinical Trials