Overview +

High-Quality Systemic Lupus Erythematosus CD19 B Cells for Immunology and Autoimmune Research

SLE CD19 B Cells are purified from peripheral blood of IRB-consented adult donors diagnosed with Systemic Lupus Erythematosus (SLE). These disease-relevant B lymphocytes support in-depth studies of immune dysregulation, autoantibody production, and chronic inflammation associated with SLE. Cryopreserved for optimal viability, these cells are ideal for translational research and therapeutic discovery.

Product Features

  • Research Use Only (RUO), CD19+ B cells
  • Isolated from SLE donors with confirmed clinical diagnosis
  • High purity and viability
  • Cryopreserved using CryoStor® CS10 media
  • Processed within 24 hours of collection
  • IRB-approved protocols and HIPAA-compliant handling

De-identified Donor Data

  • Confirmed diagnosis of SLE
  • Demographic data: age, sex assigned at birth, race/ethnicity
  • Medication and clinical history available

Applications

  • Disease-specific B cell profiling and immune phenotyping
  • Autoantibody production and BCR signaling studies
  • Autoimmune and chronic inflammatory disease modeling
  • Biomarker discovery and therapeutic target validation

Compliance and Quality Assurance

  • IRB-approved collections with 21 CFR Part 11–compliant e-consent
  • Standardized processing and cryopreservation protocols
  • HIPAA-compliant donor data protection

Ordering & Customization

Systemic Lupus Erythematosus B Cells are available in standard or custom aliquot sizes. For international shipping, documentation, or regulatory support, please contact learnmore@sanguinebio.com.

Protocols and Documentation +

Document Type Technical Document
PDF > Immune Cell Isolation

Publications +

SLE Publications

CD19+ B Cells Publications

Data and Testing +

Data and Testing with Every Sample

  • Donor demographics
  • Donor-reported allergies
  • Donor-reported infectious disease history

Questions & Answers+

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Are samples IRB approved?

1 Answer

YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.

Our complete catalog can be found here: https://sanguinebio.com/products/

Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.

Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.

Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/

Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.

YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.

Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.

YES – Unique donors can be specified and guaranteed based on your requirements.

For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/

YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.

All our samples have self-reported infectious disease testing and verified clinical diagnosis. Many of our samples have the option of electronic medical records provided and our prospective collection offers the opportunity for patient reported outcomes and surveys. Learn more here. https://sanguinebio.com/patient-reported-outcomes-pro-surveys-questionnaires/

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Compliance & Quality Assured

For quality and compliance related information, please visit Sanguine quality and compliance page.

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