Overview
High-Quality Systemic Lupus Erythematosus CD19 B Cells for Immunology and Autoimmune Research
SLE CD19 B Cells are purified from peripheral blood of IRB-consented adult donors diagnosed with Systemic Lupus Erythematosus (SLE). These disease-relevant B lymphocytes support in-depth studies of immune dysregulation, autoantibody production, and chronic inflammation associated with SLE. Cryopreserved for optimal viability, these cells are ideal for translational research and therapeutic discovery.
Product Features
- Research Use Only (RUO), CD19+ B cells
- Isolated from SLE donors with confirmed clinical diagnosis
- High purity and viability
- Cryopreserved using CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols and HIPAA-compliant handling
De-identified Donor Data
- Confirmed diagnosis of SLE
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and clinical history available
Applications
- Disease-specific B cell profiling and immune phenotyping
- Autoantibody production and BCR signaling studies
- Autoimmune and chronic inflammatory disease modeling
- Biomarker discovery and therapeutic target validation
Compliance and Quality Assurance
- IRB-approved collections with 21 CFR Part 11–compliant e-consent
- Standardized processing and cryopreservation protocols
- HIPAA-compliant donor data protection
Ordering & Customization
Systemic Lupus Erythematosus B Cells are available in standard or custom aliquot sizes. For international shipping, documentation, or regulatory support, please contact learnmore@sanguinebio.com.
Protocols and Documentation
| Document Type | Technical Document |
|---|---|
| PDF > | Immune Cell Isolation |
Publications
SLE Publications
CD19+ B Cells Publications
Data and Testing
Data and Testing with Every Sample
- Donor demographics
- Donor-reported allergies
- Donor-reported infectious disease history
Questions & Answers
1 Answer
YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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Our complete catalog can be found here: https://sanguinebio.com/products/
1 Answer
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
1 Answer
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
1 Answer
YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
1 Answer
YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
1 Answer
All our samples have self-reported infectious disease testing and verified clinical diagnosis. Many of our samples have the option of electronic medical records provided and our prospective collection offers the opportunity for patient reported outcomes and surveys. Learn more here. https://sanguinebio.com/patient-reported-outcomes-pro-surveys-questionnaires/
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Compliance & Quality Assured
For quality and compliance related information, please visit Sanguine quality and compliance page.
For privacy related information, please visit Sanguine privacy policy page.
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