Systemic Lupus Erythematosus CD4+ T Cells
Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with systemic lupus erythematosus (SLE). Ideal for studies of autoimmune dysregulation, T helper cell activation, cytokine signaling, and immune tolerance mechanisms.
Systemic Lupus Erythematosus (SLE) CD4+ T Cells
Disease-State Human CD4+ T Cells for Autoimmune Immunology Research
Human CD4+ T Cells are purified from peripheral blood of IRB-consented donors clinically diagnosed with systemic lupus erythematosus (SLE). These helper T lymphocytes play a central role in autoimmune pathogenesis through abnormal activation, cytokine dysregulation, and loss of immune tolerance. SLE CD4+ T cells are well suited for investigations of autoreactive immune responses, B cell interaction, inflammatory signaling pathways, and therapeutic modulation of systemic autoimmunity. Available cryopreserved, these cells provide high viability and reproducible performance for downstream functional and molecular assays.
Product Features
- Research Use Only (RUO) SLE CD4+ T cells
- Isolated from clinically confirmed SLE donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved collection with electronic informed consent
Donor Metadata
- Verified clinical diagnosis and health history
- Demographic data including age, sex assigned at birth, and race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune T cell activation studies
- Cytokine and immune signaling analysis
- B–T cell interaction research
- Biomarker discovery and therapeutic development
- Single-cell and transcriptomic profiling
Compliance and Quality Assurance
- IRB-approved protocols
- HIPAA-compliant donor data management
- 21 CFR Part 11–compliant e-consent system
Ordering & Customization
Available in customizable aliquot sizes. Contact learnmore@sanguinebio.com for cohort selection or study-specific requirements.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.