Systemic Lupus Erythematosus CD4+ T Cells
About:Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with systemic lupus erythematosus (SLE). Ideal for studies of autoimmune dysregulation, T helper cell activation, cytokine signaling, and immune tolerance mechanisms.
About Systemic Lupus Erythematosus CD4+ T Cells
Systemic Lupus Erythematosus (SLE) CD4+ T Cells
Disease-State Human CD4+ T Cells for Autoimmune Immunology Research
Human CD4+ T Cells are purified from peripheral blood of IRB-consented donors clinically diagnosed with systemic lupus erythematosus (SLE). These helper T lymphocytes play a central role in autoimmune pathogenesis through abnormal activation, cytokine dysregulation, and loss of immune tolerance. SLE CD4+ T cells are well suited for investigations of autoreactive immune responses, B cell interaction, inflammatory signaling pathways, and therapeutic modulation of systemic autoimmunity. Available cryopreserved, these cells provide high viability and reproducible performance for downstream functional and molecular assays.
Product Features
- Research Use Only (RUO) SLE CD4+ T cells
- Isolated from clinically confirmed SLE donors
- High purity and viability (≥90% CD4+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved collection with electronic informed consent
Donor Metadata
- Verified clinical diagnosis and health history
- Demographic data including age, sex assigned at birth, and race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune T cell activation studies
- Cytokine and immune signaling analysis
- B–T cell interaction research
- Biomarker discovery and therapeutic development
- Single-cell and transcriptomic profiling
Compliance and Quality Assurance
- IRB-approved protocols
- HIPAA-compliant donor data management
- 21 CFR Part 11–compliant e-consent system
Ordering & Customization
Available in customizable aliquot sizes. Contact learnmore@sanguinebio.com for cohort selection or study-specific requirements.
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Match your Systemic Lupus Erythematosus CD4+ T Cells with normal donor samples for comparison
Healthy CD4+ T Cells
9 In Stock View InventoryNeed a custom CD4+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.