Arthritis Synovial Fluid
Arthritis Synovial Fluid – Synovial fluid collected from IRB-consented donors with clinically confirmed arthritis. Ideal for investigating joint inflammation, immune cell activity, and cytokine expression in arthritis pathogenesis.
Arthritis Synovial Fluid for Research
Arthritis Synovial Fluid samples are collected by arthrocentesis from donors with clinically confirmed arthritis. Buy or purchase arthritis synovial fluid across inflammatory, degenerative, and crystal-induced arthropathies — pricing and availability on request.
Which Type of Arthritis Do You Need?
“Arthritis” covers conditions with fundamentally different mechanisms, and synovial fluid from each behaves differently — cell counts, dominant cell type, cytokine profile, and the presence or absence of crystals all vary. Choosing the right cohort matters more than the volume you order:
- Rheumatoid arthritis — systemic autoimmune synovitis; high leukocyte counts, neutrophil-predominant in active disease, with TNF/IL-6 driven inflammation and local RF/anti-CCP
- Osteoarthritis — degenerative rather than autoimmune; low-grade inflammation with cartilage-matrix degradation products
- Psoriatic arthritis — seronegative spondyloarthropathy with a distinct IL-17/IL-23 axis
- Gout — crystal-induced; monosodium urate crystals identifiable under polarised light, NLRP3/IL-1β driven
- Systemic lupus erythematosus — immune-complex and complement-mediated joint involvement
- Sjögren’s syndrome — articular involvement in a systemic autoimmune exocrinopathy
If your protocol calls for a broad arthritis cohort rather than a single diagnosis, we can assemble a mixed set with each donor’s specific diagnosis annotated — often the more useful design for method development, where you want the full range of the analyte rather than one disease.
Sample Characterisation
- Total and differential leukocyte count reported per sample
- Crystal identification where clinically performed
- Volume and appearance (clear, turbid, haemorrhagic) documented
- Paired serum, plasma, or PBMC from the same donor available
Product Features
- Research Use Only (RUO), fresh or frozen synovial fluid
- Samples are frozen (if requested) within 4 hours of collection
- Clinically confirmed arthritis donors, with specific diagnosis annotated
- Collected by licensed clinicians under aseptic conditions
- Processed and shipped same-day where applicable
- IRB-approved protocols and electronic informed consent
De-identified Donor Data
- Verified diagnosis of arthritis, including subtype
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Self-reported medication history and affected joints
- Disease activity and clinical history available upon request
Applications
- Cellular and cytokine profiling of synovial fluid
- Comparative studies across arthritis subtypes
- Differential diagnosis assay development
- Cartilage degradation and matrix turnover research
- Transcriptomic and proteomic analysis
- Biomarker discovery and immunophenotyping
- Therapeutic response studies and drug target validation
Quality and Compliance
- IRB-approved collections and SOP-driven processing
- 21 CFR Part 11-compliant electronic informed consent
- HIPAA-compliant donor data management
Ordering & Shipping
Arthritis Synovial Fluid samples can be shipped ambient, refrigerated, or on dry ice. For pricing, orders outside the United States, or regulatory documentation, please contact learnmore@sanguinebio.com. For healthy-donor controls and the full specimen range, see our human synovial fluid collection.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom Synovial Fluid cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.