Covid-19 Vaccinated Plasma
Powered by BiozAbout:Covid-19 Vaccinated Plasma - human plasma from donors with confirmed COVID-19 vaccination history, processed within 24 hours. Ideal for neutralizing antibody titers, vaccine platform comparison, hybrid immunity research, and variant cross-reactivity studies. Stratification by vaccine platform, dose count, booster history, and prior infection status.
About Covid-19 Vaccinated Plasma
Covid-19 Vaccinated Plasma for Vaccine Immunogenicity Research
Our Covid-19 Vaccinated Plasma is sourced from IRB-consented donors with a confirmed COVID-19 vaccination history. Each sample is processed and frozen within 24 hours of collection to preserve circulating antibodies, cytokines, and coagulation-relevant proteins for downstream vaccine immunogenicity and immune response research.
Covid-19 Vaccination Biology and Why Plasma
- SARS-CoV-2 vaccines, including mRNA (BNT162b2, mRNA-1273), viral vector, and protein subunit platforms, elicit spike-protein-specific antibody and T-cell responses that vary in magnitude and durability by platform, dose number, and time since vaccination.
- Neutralizing antibody titers, spike-specific IgG, and IgA responses are central readouts for vaccine immunogenicity studies and for assessing protection against emerging variants.
- Plasma preserves coagulation factors and complement components alongside antibody titers, supporting studies of rare vaccine-associated hematologic events as well as routine immunogenicity endpoints.
- Hybrid immunity – the combination of vaccination and prior infection – produces distinct antibody breadth and durability profiles compared to vaccination alone, making vaccination and infection history jointly important donor variables.
- Waning antibody titers over time and the emergence of immune-evasive variants have driven ongoing demand for updated bivalent and variant-specific booster response data.
Donor Stratification Available
- Vaccine platform and manufacturer (mRNA, viral vector, protein subunit)
- Number of doses and time since most recent dose
- Booster history, including bivalent or variant-specific boosters
- Prior SARS-CoV-2 infection history (hybrid immunity status)
- Age band and sex assigned at birth
- Matched unvaccinated donors available on request
Product Features
- Collected from donors with confirmed COVID-19 vaccination history
- Processed and frozen within 24 hours of collection
- Research Use Only (RUO)
- IRB-approved protocols with documented consent
- Standard and custom aliquot volumes available
De-identified Donor Data
- Vaccination confirmation, platform, and dose history
- Age, sex assigned at birth, and ethnicity
- Donor-reported allergy and infectious disease history
- Prior infection history where documented
- Additional vaccination-specific metadata available on request
Applications
- Neutralizing antibody and spike-specific IgG/IgA titer studies
- Vaccine platform comparison and durability studies
- Hybrid immunity and breakthrough infection research
- Variant cross-reactivity and immune escape assessment
- Assay development and validation for antibody and cytokine panels
Other Covid-19 Vaccinated Specimen Types
Compliance and Quality Assurance
- IRB-approved and HIPAA-compliant protocols
- Electronic informed consent with 21 CFR Part 11-compliant e-signatures
- Documentation support available for regulatory review
Ordering & Customization
Covid-19 vaccinated plasma is available in standard and custom volumes. For pricing, international orders, or documentation requirements, please email learnmore@sanguinebio.com to ensure compatibility with your country’s regulations. To compare donor availability across conditions, visit our human plasma page.
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human Plasma are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Protocols & Documentation
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Download
Plasma Isolation
Protocol for plasma separation from anticoagulated whole blood, including processing, storage, and traceability requirements.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
Plasma
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Pair with a Healthy Control
Match your Covid-19 Vaccinated Plasma with normal donor samples for comparison
Healthy Plasma
216 In Stock View InventoryNeed a custom Plasma cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.