Healthy Whole Blood
Powered by BiozAbout:Fresh Healthy Whole Blood - IRB-consented whole blood collected from clinically screened healthy donors and shipped same-day, in the anticoagulant tube your assay requires. Retains granulocytes and autologous plasma that PBMC preparation removes, making it ideal for baseline immunophenotyping, whole-blood stimulation assays, haematology validation, genomic and transcriptomic profiling, and matched controls.
About Healthy Whole Blood
Fresh Healthy Human Whole Blood for Control and Immune Profiling Research
Fresh Healthy Whole Blood is collected from IRB-consented, clinically screened healthy donors and shipped same-day for maximum freshness. Custom tubes and anticoagulants are available, so the collection matrix can be matched to the intended assay. These samples serve as baseline and matched control material for immunology, haematology, genomics, and pharmacology research.
Why Whole Blood Rather Than an Isolated Fraction
Whole blood is the only blood specimen that retains every cellular and soluble component in its native proportion, because nothing has been removed. Every downstream fraction — plasma, serum, PBMC, isolated subsets — is produced by a processing step that changes what is present.
- Density gradient PBMC preparation discards granulocytes; whole blood retains neutrophils, eosinophils, and basophils, which is essential for any study where granulocyte biology is part of the question.
- Cells remain in autologous plasma, so whole blood supports stimulation assays in which the physiological milieu — complement, immunoglobulin, acute phase proteins, plasma protein binding — is preserved rather than replaced with culture medium.
- Avoiding an isolation step avoids isolation-induced activation and marker shedding, which matters for accurate baseline immunophenotyping by flow cytometry.
- Whole blood is the required input for complete blood count and differential, and for haematology instrument and assay validation.
- It is the standard source for high-molecular-weight genomic DNA and, in RNA-stabilising tubes, for whole-blood transcriptomic profiling that captures the granulocyte-inclusive signature.
- Anticoagulant choice is not a formality: EDTA is conventional for cell counts and DNA extraction, heparin for functional culture and stimulation, citrate for coagulation work, and RNA-stabilising tubes for transcriptomics. Specifying the tube up front prevents an unusable specimen.
Donor Stratification Available
- Age band and sex assigned at birth, for demographic matching to a disease cohort
- Race and ethnicity
- Body mass index and smoking status where captured
- Medication-free donors, or donors on defined medication classes
- Blood type and infectious disease screening results, including viral serostatus where documented
- HLA typing available on request for selected inventory
- Cohorts demographically matched to a specific disease-state collection available on request
Product Features
- Fresh whole blood from clinically screened healthy donors
- Custom tubes and anticoagulants available
- Collected and shipped same-day for maximum freshness
- IRB-approved protocols with documented consent
- Research Use Only (RUO)
- Draw volumes confirmed per lot; custom volumes available on request
De-identified Donor Data
- Verified healthy status following clinical screening
- Demographic details: age, sex assigned at birth, ethnicity
- Medical history including allergies and infectious disease status
- Donor-reported medication use
Applications
- Baseline immunophenotyping of granulocyte, lymphocyte, and monocyte populations
- Whole-blood stimulation and cytokine release assays in autologous plasma
- Complete blood count reference material and haematology assay validation
- Genomic DNA extraction for genotyping and sequencing
- Whole-blood transcriptomic and gene expression analysis
- Ex vivo drug spiking, mechanism-of-action, and pharmacodynamic studies
- Platelet function and coagulation research with citrate collection
- Matched control arms for disease-state immune profiling studies
Other Healthy Donor Specimen Types
- Healthy Serum
- Healthy Plasma
- Healthy PBMC
- Healthy Leukopak
- Healthy CD3+ T Cells
- Healthy CD56+ NK Cells
Compliance and Quality Assurance
- IRB-approved protocols and electronic informed consent
- HIPAA-compliant data management
- Fast shipping with real-time tracking
Ordering & Customization
Healthy whole blood is available in standard and custom volumes and tube types. For pricing, availability, international orders, or documentation requirements, please email learnmore@sanguinebio.com to ensure compatibility with your country’s regulations. To browse other donor cohorts and collection formats, visit our human whole blood page.
Applications
- Hematology and clinical chemistry research
- Plasma, serum, and PBMC isolation
- Flow cytometry and biomarker studies
- Drug-spike and ex vivo stimulation assays
Product Features
- Research Use Only (RUO), human whole blood
- Collected from screened, consented donors
- Available in EDTA, sodium heparin, ACD, or citrate anticoagulants
- Shipped fresh under temperature-controlled conditions
- Drawn and shipped same day of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human Whole Blood are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Whole Blood
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
Ask a Question
Need a custom Whole Blood cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.