Type 1 Diabetes CD8+ T Cells
About:Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with Type 1 diabetes. Suitable for research investigating antigen-specific cytotoxic responses involved in pancreatic beta-cell destruction.
About Type 1 Diabetes CD8+ T Cells
Type 1 Diabetes CD8+ T Cells
Disease-State Human CD8+ T Cells for Autoimmune and Metabolic Research
Human CD8+ T Cells are purified from peripheral blood of IRB-consented donors clinically diagnosed with Type 1 diabetes (T1D). CD8+ cytotoxic T lymphocytes are key mediators of autoimmune beta-cell destruction and antigen-specific immune activation in T1D pathogenesis. These cells support investigations into cytotoxic immune mechanisms, immune tolerance breakdown, and therapeutic strategies targeting autoimmune diabetes. Available cryopreserved, these cells provide high viability and consistent functional performance for in vitro assays and molecular profiling.
Product Features
- Research Use Only (RUO), CD8 positive T cells
- Isolated from clinically confirmed Type 1 diabetes donors
- High purity and viability (≥90% CD8+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and health history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Applications
- Autoimmune antigen recognition studies
- Beta-cell cytotoxicity assays
- Immune tolerance research
- Cytokine and signaling pathway analysis
- Single-cell and transcriptomic profiling
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Applications
- Immunology and translational research
- Biomarker discovery and validation
- Drug screening and assay development
- Vaccine and infectious disease research
Product Features
- Research Use Only (RUO), CD8+ T Cells
- Sourced from screened, consented donors
- Processed under validated SOPs
- QC tested for purity, viability, and sterility
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Need a custom CD8+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.