Frontotemporal Dementia PBMC
About: Frontotemporal Dementia PBMC - IRB-consented PBMC samples collected from donors diagnosed with Frontotemporal Dementia. Suitable for profiling peripheral immune cells involved in neuroinflammation and neurodegeneration.
Frontotemporal Dementia PBMC
Frontotemporal Dementia PBMC is collected from IRB-consented donors diagnosed with clinically confirmed Frontotemporal Dementia (FTD). These peripheral blood mononuclear cell (PBMC) samples are ideal for profiling peripheral immune cells involved in neuroinflammation and neurodegeneration. PBMCs from FTD donors are valuable for studying immune dysregulation, transcriptomics, and neurodegenerative disease mechanisms.
Product Features
- Cryopreserved, clinically verified FTD PBMC samples
- Cryopreserved to ensure stability and long-term storage
- Research Use Only (RUO)
De-identified Donor Data
- Clinically confirmed FTD diagnosis
- Donor demographics: age, sex assigned at birth, ethnicity
- Medical and treatment history available when applicable
Applications
- Profiling peripheral immune cells involved in neuroinflammation and neurodegeneration
- Biomarker discovery and validation
- Transcriptomic, proteomic, or functional studies
- Custom assay development and disease modeling
Compliance and Quality
- IRB-approved collection and electronic informed consent
- HIPAA-compliant donor data handling
Ordering and Customization
Frontotemporal Dementia PBMC is available in standard and custom volumes. Contact learnmore@sanguinebio.com for international requests or documentation needs.
Protocols & Documentation
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PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.