Human PBMC Samples
Powered by BiozHuman PBMCs for Research:
Human PBMC samples are collected from healthy and clinically confirmed disease-state donors, then cryopreserved to preserve viability and function. Sanguine’s PBMCs are designed to support a wide range of research applications, from immune profiling and cytokine analysis to cell-based assays and therapeutic development.
About Human PBMC Samples
Human PBMC Samples for Research
Human PBMCs are sourced from healthy and disease-state donors and processed under controlled conditions to support high-quality research. These cryopreserved peripheral blood mononuclear cells enable studies in immune function, cytokine response, biomarker discovery, cell therapy research, and therapeutic screening.
Whether you need PBMCs as matched controls, disease-state comparators, or custom donor-defined samples, Sanguine helps research teams source PBMCs aligned to protocol requirements and downstream assay needs.
What Is a PBMC?
Human PBMCs (peripheral blood mononuclear cells) are the round-nucleus immune cells — lymphocytes, monocytes, and dendritic cells — isolated from whole blood or a leukopak, and one of the most widely used starting materials in immunology and cell therapy research. For a full primer, see our guide to human PBMCs.
Product Features
- Research use only cryopreserved human PBMCs
- Sourced from healthy and disease-state donors
- Available in cell counts ranging from 5 million to 2 billion
- Processed within 24 hours of collection
- Preserved using CryoStor CS10 freezing media
- Designed to support cell viability and functional assays
- IRB-approved protocols and electronic informed consent
- Screening and bulk-order support available for larger PBMC programs
De-identified Donor Data
Available donor-level information helps researchers select PBMC samples that align to study design and population requirements.
- Donor demographics including age, sex assigned at birth, and race/ethnicity
- Self-reported allergies and infectious disease history
- Healthy donor and disease-state context where applicable
- Additional donor-specific data available upon request
- Study-specific donor requirements may be supported for custom programs
Applications
Human PBMCs support a broad range of immunology and translational research workflows.
- Biomarker discovery and validation
- Drug screening and therapeutic development
- Immune pathway analysis
- Cytokine and functional immune assays
- Transcriptomic and proteomic profiling
- Cell-based assay development
- Matched control and disease-state comparison studies
Disease-State & Patient PBMCs
Sanguine supplies disease-state PBMCs and patient PBMCs from donors with confirmed diagnoses across 100+ conditions — spanning autoimmune, oncology (cancer), metabolic, neurological, and infectious disease. These are the same peripheral blood mononuclear cells researchers use for biomarker discovery, immune profiling, and drug screening in specific disease contexts. Select a condition from the menu above, or browse common cohorts below.
- Autoimmune & inflammatory PBMCs — ulcerative colitis / IBD, Sjögren’s syndrome, systemic sclerosis, and atopic dermatitis — plus lupus and rheumatoid arthritis cohorts on request.
- Cancer (oncology) PBMCs — patient PBMCs from solid-tumor and hematologic cancers, including esophageal cancer and lymphoma.
- Metabolic, neurology & infectious-disease PBMCs — type 2 diabetes, interstitial lung disease, anemia, and COVID-19.
Need a condition not listed? We run custom disease-state PBMC collections built to your inclusion/exclusion criteria — request a quote.
For related products, see our human leukopak and human whole blood.
Quality and Compliance
- IRB-approved collections and protocols
- 21 CFR Part 11-compliant electronic informed consent
- HIPAA-compliant donor data protection
- Controlled processing workflows designed to support PBMC quality
- Documentation available for qualified research programs
Ordering & Shipping
Human PBMC samples are shipped on dry ice and are available in multiple cryopreserved configurations to support a range of research needs. If your project requires custom aliquots, larger bulk orders, or international documentation, our team can help identify the right fulfillment path. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com.
Buy Human PBMCs for Research
Sanguine is a trusted supplier of human PBMCs for research, offering healthy and disease-state PBMC samples from a community of 70,000+ donors. Purchase fresh or cryopreserved patient PBMCs with full donor data, or commission a custom PBMC collection built to your inclusion/exclusion criteria. Browse in-stock PBMC samples above or request a quote to buy PBMCs for your study.
Frequently Asked Questions About Buying PBMCs
How do I buy PBMCs for research?
Browse the in-stock human PBMC samples above or request a quote. Sanguine supplies fresh and cryopreserved PBMCs from healthy and disease-state donors, with custom collections available to your study criteria.
How much do human PBMCs cost?
PBMC pricing depends on cell count, donor type (healthy or disease-state), and fresh vs. cryopreserved format. Request a quote for current PBMC prices and volume discounts on bulk orders.
Do you offer disease-state and patient PBMCs?
Yes. We provide disease-state and patient PBMC samples across 100+ confirmed conditions, plus healthy controls — see the disease-state PBMC list above or request a custom cohort.
Are PBMC samples available for sale fresh and cryopreserved?
Yes. Human PBMC samples are available for purchase in both fresh and cryopreserved formats, in cell counts ranging from 5 million to 2 billion per vial.
Applications
- Immunology and translational research
- Biomarker discovery and validation
- Drug screening and assay development
- Vaccine and infectious disease research
Product Features
- Research Use Only (RUO), PBMC
- Sourced from screened, consented donors
- Processed under validated SOPs
- QC tested for purity, viability, and sterility
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human PBMC are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Protocols & Documentation
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Download
PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Download
Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Download
Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
Ask a Question
Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.