Down Syndrome Whole Blood
Whole blood from donors with confirmed Down syndrome (trisomy 21). Useful for chromosome 21 gene-dosage research and immune dysregulation biomarker studies.
Down Syndrome Whole Blood for Research
Down syndrome (trisomy 21) is a genetic condition associated with distinct immune dysregulation and elevated risk for autoimmune and hematologic conditions. Sanguine collects fresh whole blood from IRB-consented donors with a clinically confirmed Down syndrome diagnosis for genomics and immunology research.
Product Features
- Fresh whole blood from donors with confirmed Down syndrome
- Custom anticoagulants and collection tubes available
- Same-day collection and shipment
- Research Use Only (RUO)
De-identified Donor Data
- Physician-confirmed Down syndrome diagnosis
- Demographics: age, sex assigned at birth, ethnicity
- Relevant medical and comorbidity history
Applications
- Chromosome 21 gene-dosage and genomic research
- Immune dysregulation and autoimmune biomarker studies
- Gene expression and transcriptomic analysis (PBMC applications)
- Drug response and mechanism-of-action studies
Also Available
Down syndrome samples are also available as PBMC for cell-based immune assays – contact us to discuss the right specimen type for your study.
Compliance and Quality
- IRB-approved protocols and electronic informed consent
- HIPAA-compliant donor data handling
Ordering and Customization
Down syndrome whole blood is available in standard and custom volumes. Email learnmore@sanguinebio.com for international orders or documentation requirements.
Whole Blood
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom Whole Blood cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.