Human Papillomavirus HPV Serum
Human Papillomavirus HPV Serum - Human serum samples collected from clinically confirmed HPV donors. Ideal for detecting antibodies, studying seroconversion, and evaluating vaccine efficacy and immune memory.
Human Papillomavirus (HPV) Serum for Research
Our HPV Serum is sourced from IRB-consented donors with a clinically confirmed HPV diagnosis. Each sample is processed and frozen within 24 hours of collection to ensure consistency and high quality for antibody detection, seroconversion studies, and vaccine efficacy and immune memory research.
Serum or Plasma? Choose by Assay Type
For HPV work the two matrices answer different questions, and picking the wrong one is a common and costly mistake:
- Serum (this page) — the matrix for serology: anti-L1 VLP antibodies, neutralising antibody titres, seroconversion series, and vaccine-response work
- Plasma — the matrix for molecular work: circulating HPV DNA, cell-free and tumour-derived DNA, and viral load quantification
If your assay measures an antibody, order serum. If it amplifies viral nucleic acid, order plasma.
Donor Stratification Available
- HPV type — high-risk types including 16 and 18, or low-risk types, where genotyped
- Vaccination status — unvaccinated, or vaccinated (bivalent, quadrivalent, or nonavalent), which is essential context since vaccine-induced and natural-infection antibody profiles differ substantially in titre and breadth
- Antibody status — anti-L1 seropositive or seronegative, with titre where tested
- Clinical stage — infection, cytological abnormality, CIN grade, or invasive disease where documented
- Anatomical site — cervical, oropharyngeal, anogenital
- Matched seronegative controls available
Product Features
- Collected from donors with clinically confirmed HPV
- Research Use Only (RUO)
- IRB-approved protocols with documented consent
- Custom aliquot volumes available on request
- Defined-titre samples available for assay calibration
De-identified Donor Data
- Diagnosis confirmation, with HPV genotype where available
- Age, sex assigned at birth, and ethnicity
- Vaccination history where recorded
- Donor-reported allergy and infectious disease history
Applications
- Anti-L1 VLP antibody assay development and validation
- Neutralising antibody and pseudovirion assay work
- Seroconversion and immune durability studies
- Vaccine efficacy and immune memory research
- Serological reference panel and positive control preparation
- Biomarker discovery for HPV-associated disease
- Serum cytokine and protein profiling
- Therapeutic candidate screening and validation
Other HPV Specimen Types
Matched material from HPV-positive donors is available as HPV plasma (for molecular work), whole blood, and HPV leukopak. For HPV-associated malignancy see cervical cancer serum.
Compliance and Quality Assurance
- IRB-approved and HIPAA-compliant protocols
- Electronic informed consent with 21 CFR Part 11 – compliant e-signatures
- Documentation support available for regulatory review
Ordering and Customization
HPV serum is available in standard and custom volumes. For pricing, international orders, or documentation requirements, please email learnmore@sanguinebio.com to ensure compatibility with your country’s regulations. For the full specimen range, see our human serum collection.
Protocols & Documentation
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Download
Serum Isolation
Protocol for serum preparation from whole blood, including collection handling, clarification, and quality documentation.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
Serum
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – all our products are research use only (RUO).
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You can find our full product catalog here.
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: Quality and Compliance
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom Serum cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.