Human Papillomavirus HPV Serum

About Human Papillomavirus HPV Serum

Human Papillomavirus (HPV) Serum for Research

Our HPV Serum is sourced from IRB-consented donors with a clinically confirmed HPV diagnosis. Each sample is processed and frozen within 24 hours of collection to ensure consistency and high quality for antibody detection, seroconversion studies, and vaccine efficacy and immune memory research.

Serum or Plasma? Choose by Assay Type

For HPV work the two matrices answer different questions, and picking the wrong one is a common and costly mistake:

• Serum (this page) — the matrix for serology: anti-L1 VLP antibodies, neutralising antibody titres, seroconversion series, and vaccine-response work
• Plasma — the matrix for molecular work: circulating HPV DNA, cell-free and tumour-derived DNA, and viral load quantification

If your assay measures an antibody, order serum. If it amplifies viral nucleic acid, order plasma.

Donor Stratification Available

• HPV type — high-risk types including 16 and 18, or low-risk types, where genotyped
• Vaccination status — unvaccinated, or vaccinated (bivalent, quadrivalent, or nonavalent), which is essential context since vaccine-induced and natural-infection antibody profiles differ substantially in titre and breadth
• Antibody status — anti-L1 seropositive or seronegative, with titre where tested
• Clinical stage — infection, cytological abnormality, CIN grade, or invasive disease where documented
• Anatomical site — cervical, oropharyngeal, anogenital
• Matched seronegative controls available

Product Features

• Collected from donors with clinically confirmed HPV
• Research Use Only (RUO)
• IRB-approved protocols with documented consent
• Custom aliquot volumes available on request
• Defined-titre samples available for assay calibration

De-identified Donor Data

• Diagnosis confirmation, with HPV genotype where available
• Age, sex assigned at birth, and ethnicity
• Vaccination history where recorded
• Donor-reported allergy and infectious disease history

Applications

• Anti-L1 VLP antibody assay development and validation
• Neutralising antibody and pseudovirion assay work
• Seroconversion and immune durability studies
• Vaccine efficacy and immune memory research
• Serological reference panel and positive control preparation
• Biomarker discovery for HPV-associated disease
• Serum cytokine and protein profiling
• Therapeutic candidate screening and validation

Other HPV Specimen Types

Matched material from HPV-positive donors is available as HPV plasma (for molecular work), whole blood, and HPV leukopak. For HPV-associated malignancy see cervical cancer serum.

Compliance and Quality Assurance

• IRB-approved and HIPAA-compliant protocols
• Electronic informed consent with 21 CFR Part 11 – compliant e-signatures
• Documentation support available for regulatory review

Ordering and Customization

HPV serum is available in standard and custom volumes. For pricing, international orders, or documentation requirements, please email learnmore@sanguinebio.com to ensure compatibility with your country’s regulations. For the full specimen range, see our human serum collection.