APECED PBMC
About: APECED PBMC samples are collected from clinically confirmed autoimmune polyendocrinopathy-candidiasis-ectodermal Dystrophy (APECED) donors and cryopreserved for immunological and genetic research. Ideal for studying inflammatory pathways, immune cell responses, and therapeutic development in APECED.
| Lot Number | Condition | Cell Count (M) | Race/Ethnicity | Age | Gender | Country of Collection | Medications | Vials | Price | Action |
|---|---|---|---|---|---|---|---|---|---|---|
| 74337 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 75 | Male | United States (US) |
Humalog Cartridge 3mL 25 units QD Cyanocobalamin 10000mcg/ml Inj. 1 mL every 3 weeks Potassium Cl 20meq ER Tablets 1 QD Calcitriol 0.25 mcg Capsules 1 QD Fludrocortisone 0.1 mg Tablets 1 QD Levothyroxine 0.05mg (50mcg) Tablets 1 QD Hydrocortisone 5mg Tablets 15 mg Q.A.M and 5mg Q.P.M. Calcium citrate-vitamin D 315 mg-250 unit 2 QD Iron (Ferrous Sulfate) 325 (65 Fe) MG Tablet 1 QD Magnesium oxide 400 mg tablet 1 QD
|
8 | ||
| 71642 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 73 | Female | United States (US) |
Calcium Carbonate 600mg 1.5 tabs QD Synthroid 127 mcg QD Calcitriol 25 mcg M-F QD Vitamin D 2000 IU QD Multivitamin QD Toprol XL 50 mg QD Benazepril 20 mg QD - ACE INHIBITOR Atorvastatin 20 mg QD Co- Enzyme 400 mg QD Mega Red 500 mg QD Fenofibrate 160 mg QD Adalat/ Nifedipine ER 30 mg QD Chlorthalidone 25 QD Tylenol 500 mg 2 tabs BID
|
4 | ||
| 62258 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian Hispanic/Latino | 46 | Male | United States (US) |
Hydrocortisone 5mg tablets 6 daily Fludrocortisone .1mg QD Levothyroxine .175 mcg QD Calcitriol .25mcg BID Budesonide .5 mg using for limited time
|
2 | ||
| 61039 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 75 | Male | United States (US) |
Humalog Cartridge 3mL 25 units QD Cyanocobalamin 10000mcg/ml Inj. 1 mL every 3 weeks Potassium Cl 20meq ER Tablets 1 QD Calcitriol 0.25 mcg Capsules 1 QD Fludrocortisone 0.1 mg Tablets 1 QD Levothyroxine 0.05mg (50mcg) Tablets 1 QD Hydrocortisone 5mg Tablets 15 mg Q.A.M and 5mg Q.P.M. Calcium citrate-vitamin D 315 mg-250 unit 2 QD Iron (Ferrous Sulfate) 325 (65 Fe) MG Tablet 1 QD Magnesium oxide 400 mg tablet 1 QD
|
6 | ||
| 61037 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 64 | Female | United States (US) |
Fludrocortisone 1 mg QD calcitrol 25 BID hydrocortisone 10 mg BID magnesium oxide 400 mg BID VD3 25mcg (1000iu) QD
|
4 | ||
| 62688 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 31 | Female | United States (US) |
Cortef (Hydrocortison) 5mg - 1 tab PO TID (with an additional 1/2 tab in the morning): 7.5mg/5mg/5mg NatPara (Parathyroid Hormone Injection) - 75mcg QOD & 50 mcg QOD (switch dosage every other day, odd days are 75 and even days are 50mcg) Loestrin 24FE (hormone replacement) - 1 tab QD (pm) Fludrocortisone 0.1mg - 1/2 tab PO AD (am) Cozaar (Losartan) 50mg - 1 Tab PO QD (am) Imuran (Azathioprine) 50mg - 1 Tab PO QD (am) Meriva (Curcumin) 1000mg - PO BID Zinc Sulfate 220mg - 1 tab PO QD (am) Vitamin D3 1000IU - 1 Tab QD (am) Birth Control
|
3 | ||
| 59881 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 31 | Female | United States (US) |
Cortef (Hydrocortison) 5mg - 1 tab PO TID (with an additional 1/2 tab in the morning): 7.5mg/5mg/5mg NatPara (Parathyroid Hormone Injection) - 75mcg QOD & 50 mcg QOD (switch dosage every other day, odd days are 75 and even days are 50mcg) Loestrin 24FE (hormone replacement) - 1 tab QD (pm) Fludrocortisone 0.1mg - 1/2 tab PO AD (am) Cozaar (Losartan) 50mg - 1 Tab PO QD (am) Imuran (Azathioprine) 50mg - 1 Tab PO QD (am) Meriva (Curcumin) 1000mg - PO BID Zinc Sulfate 220mg - 1 tab PO QD (am) Vitamin D3 1000IU - 1 Tab QD (am) Birth Control
|
10 | ||
| 55084 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 28 | Female | United States (US) |
-calcium carbonate 250mg 4x/day (they are 500mg capsules that I cut in half) -zinc 50mg 1x/day -biotin 5000mcg 1x/day -fludrocortisone (florinef) 0.1mg tab 1x/day -hydrocortisone (cortef EQ) 10mg 1x/day, 5mg 1x/day, and .25mg 1x/day -calcitriol (rocaltrol eq) .25mcg capsule 4x/day -ferrous sulfate 325mg tab 2x/day -cetirizine (Zyrtec) 10mg 1x/day -levothyroxine (synthroid) 112mcg 1x/day -cholecalcifer (vitamin d3) 400IU (10mcg), 2 tablets 1x/day -EE/Noret FE 0.03/1.5mg loestrin FE EQ 1 tablet 1x/day for 9 weeks, off one week -cyclosorine (restasis) 0.05% opt so 30s 1 drop in each eye 2x/day -hydrocortisone (solucortef) adult kit for emergencies
|
21 | ||
| 48799 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian Hispanic/Latino | 46 | Male | United States (US) |
Hydrocortisone 5mg tablets 6 daily Fludrocortisone .1mg QD Levothyroxine .175 mcg QD Calcitriol .25mcg BID Budesonide .5 mg using for limited time
|
7 | ||
| 48803 | APECED (Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) | 10M | Caucasian | 73 | Female | United States (US) |
Calcium Carbonate 600mg 2 tabs QD Synthroid .200 mcg QD Calcitriol 25 mcg M-F QD Vitamin D 2000 IU QD Multivitamin QD Toprol XL 200 mg QD Benazepril 20 mg QD Lovastatin 20 mg QD Co- Enzyme 400 mg QD Probiotics QD Mega Red 500 mg QD Fenofibrate 160 mg QD Adalat/ Nifedipine ER 30 mg QD
|
5 |
High-Quality APECED PBMC for Research
APECED PBMC products are sourced from donors clinically diagnosed with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) and processed under stringent conditions to support genetic and immunology research. These cryopreserved peripheral blood mononuclear cells (PBMCs) enable studies on immune dysregulation, cytokine response, and therapeutic screening for APECED.
Product Features
- Research Use Only (RUO), cryopreserved PBMC
- Clinically confirmed Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) donors
- Available in cell counts ranging from 5 million to 2 billion
- Processed within 24 hours of collection
- Stored using CryoStor® CS10 freezing media
- IRB-approved protocols and electronic informed consent
- Screen LeukoLot™ available prior to bulk orders
De-identified Donor Data
- Verified Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) diagnosis
- Donor demographics: age, sex assigned at birth, race/ethnicity
- Self-reported allergies and infectious disease history
- APECED-specific data available upon request
Applications
- Biomarker discovery and validation
- Drug screening and therapeutic development
- Immune pathway analysis in APECED pathophysiology
- Transcriptomic and proteomic profiling
Quality and Compliance
- IRB-approved collections and protocols
- 21 CFR Part 11 – compliant e-consent system
- HIPAA-compliant donor data protection
Ordering & Shipping
APECED PBMC samples are shipped on dry ice and available in custom aliquots. For international orders or regulatory requirements, please contact learnmore@sanguinebio.com to confirm documentation and compliance needs.
Protocols & Documentation
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Download
PBMC Isolation from Whole Blood
Standard operating procedure for isolating peripheral blood mononuclear cells from whole blood using density-gradient separation.
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Download
Immune Cell Isolation
Guidelines for isolating immune cell populations with validated enrichment steps, purity checkpoints, and documentation.
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Download
Choosing the Right PBMC Configuration
Reference guide comparing PBMC formats, cryopreservation states, and study-fit recommendations for your application.
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Download
Thawing Cryopreserved PBMC
Validated thawing protocol to recover viable cryopreserved PBMCs while minimizing activation and loss of function.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
PBMC
Frequently Asked Questions
1 Answer
YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
1 Answer
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
1 Answer
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
1 Answer
YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom PBMC cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.