Rheumatoid arthritis CD8+ T Cells
About: Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with rheumatoid arthritis. Ideal for investigations of inflammatory immune activation and cytotoxic T cell–mediated autoimmune mechanisms.
Rheumatoid Arthritis CD8+ T Cells
CD8+ T Cells for Inflammatory and Autoimmune Research
Human CD8+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with rheumatoid arthritis. CD8+ cytotoxic lymphocytes contribute to chronic synovial inflammation and immune-mediated joint damage. These cells are suitable for studies investigating inflammatory signaling, immune activation pathways, and development of targeted immunotherapies.
Product Features
- Research Use Only (RUO), CD8 positive T cells
- Isolated from clinically confirmed rheumatoid arthritis donors
- High purity and viability (≥90% CD8+ cells)
- Cryopreserved in CryoStor® CS10 media
- Processed within 24 hours of collection
- IRB-approved protocols with electronic informed consent
Donor Metadata
- Confirmed diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Applications
- Inflammatory cytokine profiling
- Cytotoxic signaling studies
- Immunotherapy evaluation
- Functional immune assays
- Transcriptomic analysis
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11–compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human CD8+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.
Frequently Asked Questions
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YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.
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YES – with the exception of GMP leukopaks, all our products are research use only (RUO).
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Our complete catalog can be found here: https://sanguinebio.com/products/
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Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
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Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
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Sanguine offers flexible prospective colleciton services to tailored to fit your research. For more information and request a quote, please see: https://sanguinebio.com/prospective-biospecimen-collection-services/
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Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
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YES – we have in-stock inventory which can be found here https://sanguinebio.com/products/?pro_inventory=inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
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Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
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YES – Unique donors can be specified and guaranteed based on your requirements.
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For information about sample quality, please see: https://sanguinebio.com/quality-and-compliance/
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YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Ask a Question
Need a custom CD8+ T Cells cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.