Rheumatoid arthritis CD4+ T Cells

Rheumatoid Arthritis CD4+ T Cells

Disease-State CD4+ T Cells for Inflammatory and Autoimmune Research

Human CD4+ T Cells are isolated from peripheral blood of IRB-consented donors diagnosed with rheumatoid arthritis. CD4+ helper T lymphocytes contribute to chronic synovial inflammation and immune-mediated joint damage. These cells are suitable for studies investigating inflammatory signaling, immune activation pathways, and development of targeted immunotherapies.

Product Features

  • Research Use Only (RUO), CD4 positive T cells
  • Isolated from clinically confirmed rheumatoid arthritis donors
  • High purity and viability (≥90% CD4+ cells)
  • Cryopreserved in CryoStor® CS10 media
  • Processed within 24 hours of collection
  • IRB-approved protocols with electronic informed consent

Donor Metadata

  • Confirmed diagnosis and clinical history
  • Demographic data: age, sex assigned at birth, race/ethnicity
  • Medication and treatment background when available

Applications

  • Inflammatory cytokine profiling
  • Autoimmune signaling studies
  • Immunotherapy evaluation
  • Functional immune assays
  • Transcriptomic analysis

Compliance and Quality Assurance

  • IRB-approved collections and standardized procedures
  • 21 CFR Part 11–compliant e-consent system
  • HIPAA-compliant data management

Ordering & Customization

Human CD4+ T Cells are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability.

Frequently Asked Questions

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Are samples IRB approved?

1 Answer

YES – All collections are conducted under IRB-approved protocols and electronic informed consent. Sanguine utilizes Advarra and WCG IRB for oversight.

YES – all our products are research use only (RUO).

Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.

Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.

Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.

Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.

YES – we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.

Each sample from a different individual – Unique donor means each sample comes from a different person, ensuring biological diversity in your study.

YES – Unique donors can be specified and guaranteed based on your requirements.

For information about sample quality, please see: Quality and Compliance

YES – “IRB-approved collection protocols” and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.

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Need a custom CD4+ T Cells cohort?

Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.

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