Allergy Serum
About:Allergy Serum - Human allergy serum samples collected from clinically confirmed Allergy donors. Ideal for dermatology, cytokine profiling, and inflammation-related research.
About Allergy Serum
Human Allergy Serum for Research
Our Allergy Serum is sourced from IRB-consented donors with a clinically confirmed allergy diagnosis. Each sample is processed and frozen within 24 hours of collection to ensure consistency and high quality for allergy, IgE, and immunology research. Allergy serum is available in standard and custom volumes — request pricing and cost information below.
IgE: What Makes Allergy Serum Useful
Type I allergy is IgE-mediated, and serum is where that IgE is measurable — which makes allergy serum the primary material for allergen diagnostics and immunotherapy research rather than a surrogate. Available characterisation includes:
- Total IgE — quantified in IU/mL where tested
- Allergen-specific IgE (sIgE) — specified to your allergen of interest, with class or kU/L values where available
- Defined titre ranges — high-titre donors for positive controls, or samples selected to a target concentration window for assay calibration
- Component-resolved data — individual allergen components rather than whole-extract results, where tested
- Tryptase — for mast cell activation and anaphylaxis research
- Matched non-atopic controls — donors with low total IgE and no sensitisation
Allergen Cohorts Available
- Food — peanut, tree nut, milk, egg, shellfish, wheat, soy
- Aeroallergen — dust mite, cat, dog, grass pollen, tree pollen, ragweed, Aspergillus
- Alpha-gal — delayed mammalian meat allergy; see alpha-gal syndrome serum
- Venom and drug — available as custom collections
- Polysensitised donors — reactive to multiple allergens, useful for multiplex panel validation
Product Features
- Collected from donors with clinically confirmed allergy
- Research Use Only (RUO)
- IRB-approved protocols with documented consent
- Custom aliquot volumes available on request
- Single-donor and pooled formats
De-identified Donor Data
- Diagnosis confirmation, including specific allergen where identified
- Diagnostic method — sIgE testing, skin prick test, or oral food challenge
- Age, sex assigned at birth, and ethnicity
- Donor-reported allergy and infectious disease history
- Atopic comorbidities — asthma, atopic dermatitis, allergic rhinitis
Applications
- Total and allergen-specific IgE immunoassay development and validation
- Multiplex allergen panel and component-resolved diagnostic development
- Positive control and calibrator preparation
- Allergen immunotherapy research, including IgG4 blocking antibody studies
- Basophil activation test (BAT) serum-transfer work
- Biomarker discovery for allergy
- Serum cytokine and protein profiling
- Therapeutic candidate screening and validation, including anti-IgE approaches
Other Allergy Specimen Types
Matched material from allergy donors is available as allergy plasma, whole blood, and PBMC. For related atopic cohorts see atopic dermatitis serum and chronic spontaneous urticaria plasma.
Compliance and Quality Assurance
- IRB-approved and HIPAA-compliant protocols
- Electronic informed consent with 21 CFR Part 11 – compliant e-signatures
- Documentation support available for regulatory review
Ordering and Customization
Allergy serum is available in standard and custom volumes. For pricing, international orders, or documentation requirements, please email learnmore@sanguinebio.com to ensure compatibility with your country’s regulations. For the full specimen range, see our human serum collection.
Donor Metadata
- Verified diagnosis and clinical history
- Demographic data: age, sex assigned at birth, race/ethnicity
- Medication and treatment background when available
Compliance and Quality Assurance
- IRB-approved collections and standardized procedures
- 21 CFR Part 11-compliant e-consent system
- HIPAA-compliant data management
Ordering & Customization
Human Serum are available in customizable aliquot sizes. For international orders or documentation needs, please contact learnmore@sanguinebio.com to confirm requirements and availability. We also work with multiple ordering platforms and distributors, learn more here.
Protocols & Documentation
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Download
Serum Isolation
Protocol for serum preparation from whole blood, including collection handling, clarification, and quality documentation.
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Informed Consent Form (ICF)
Available upon request — confirms donor consent for research use and downstream commercialization.
Serum
Where can I find your complete catalog?
You can find our full product catalog here.
How long can samples be stored?
Storage depends on sample type but often cryopreserved samples stored in liquid nitrogen can be stored for years.
What customization options are available?
Extensive customization is available. To discuss your project request a quote or email us at learnmore@sanguinebio.com.
Do you offer prospective collections?
Sanguine offers flexible prospective collection services tailored to fit your research. For more information and to request a quote, please see: our prospective biospecimen collection services page.
What is the turnaround time for custom collections?
Timelines depend on condition, sample type, and I/E criteria but we often start collection within 2 weeks of signed agreement.
Do you have samples in stock?
YES - we have in-stock inventory. You can also email us at learnmore@sanguinebio.com as we continually get new samples in our inventory.
What does unique donor mean?
Each sample from a different individual - Unique donor means each sample comes from a different person, ensuring biological diversity in your study.
Are samples collected under IRB-approved protocols?
YES - "IRB-approved collection protocols" and IRB approval documentation available upon request. Sanguine utilizes two internationally-recognized IRBs (Advarra and WCG IRB) for review and approval.
Frequently Asked Questions
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Pair with a Healthy Control
Match your Allergy Serum with normal donor samples for comparison
Healthy Serum
100 In Stock View InventoryNeed a custom Serum cohort?
Our scientific team can scope prospective collections with donor-specific I/E criteria, typically starting within 2 weeks of agreement.